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- Symptoms: the corneal changes are rarely of any visual significance.
- Symmetric, bilateral, whorl-like pattern of powdery, white, yellow or brown corneal epithelial deposits
- Appears in a vortex fashion in the inferocentral cornea and swirls outwards sparing the limbus
- Occurs in Fabry's disease and in patients being treated with a variety of drugs including amiodarone, chloroquine, amodiaquine, meperidine, indomethacin, chlorpromazine and tamoxifen.