Salzmann's Nodules

Salzmann's Nodular Degeneration
  • May develop from previous ocular inflammatory conditions such as following corneal surgery, interstitial keratitis, trachoma and contact lens wear.

Clinical Features

  • Symptoms: usually asymptomatic, but may cause decreased vision if located centrally
  • Signs:
    • Noninflammatory
    • Superficial, elevated multiple bluish-white nodules
    • Located at corneal mid-periphery
    • May increase in number, elevation, and size


  • Observation
  • Simple excision of the lesion
  • Excimer laser phototherapeutic keratectomy