Irvine-Gass Syndrome

Pseudophakic cystoid macular edema demonstrating obscuration of macular detail.
  • Fluid accumulation within the sensory retina in the macular area.
  • Common complication following uneventful cataract surgery.

Clinical Features

  • Symptoms:
    • Decreased or blurred vision depends on the extent of the edema
    • Hyperopic refractive shift
  • Signs:
    • Ophthalmoscope examination shows macular detail obscuration
    • Anterior segment vitreous strands or incarceration may be seen if cataract surgery was complicated with vitreous loss
  • Fluorescein angiography demonstrates typical petaloid appearance of fluorescein dye leakage during angiography.


  • Observation
  • Topical or sub-tenon's steroids
  • Vitrectomy in refractory CME caused by vitreous incarceration