Pulmonary, Allergy, and Critical Care

Lung Transplantation Clinical Trials and Studies

Clinical Trials

A Phase III, Prospective, Multicenter, Randomized, Controlled Clinical Trial to Demonstrate the Effectiveness and Safety of Liposomal Cyclosporine A (L-CsA) Inhalation Solution Delivered via the PARI Investigational eFlow Device plus Standard of Care versus Standard of Care Alone in the Treatment of Bronchiolitis Obliterans Syndrome in Patients post-Single Lung Transplantation

  • Protocol No: BT-LCsA-301-SLT
  • Sponsor: BREATH Therapeutics Inc. 
  • Principal Investigator: Selim Arcasoy

A Phase III, Prospective, Multicenter, Randomized, Controlled Clinical Trial to Demonstrate the Effectiveness and Safety of Liposomal Cyclosporine A (L-CsA) Inhalation Solution Delivered via the PARI Investigational eFlow Device plus Standard of Care versus Standard of Care Alone in the Treatment of Bronchiolitis Obliterans Syndrome in Patients post Double Lung Transplantation

  • Protocol No: BT-LCsA-302-DLT
  • Sponsor: BREATH Therapeutics Inc.
  • Principal Investigator: Selim Arcasoy

A Phase III, Multicenter, Open-Label, Extension Clinical Trial to Demonstrate the Effectiveness and Safety of Liposomal Cyclosporine A (L-CsA) Inhalation Solution Delivered via the PARI Investigational eFlow Device plus Standard of Care in the Treatment of Bronchiolitis Obliterans Syndrome in Patients post Single or Double Lung Transplantation

  • Protocol No: BT-LCsA-303-FU (BOSTON-3)
  • Sponsor: BREATH Therapeutics Inc
  • Principal Investigator: Selim Arcasoy

Extracorporeal Photopheresis for the Management of Progressive Bronchiolitis Obliterans Syndrome in Medicare-Eligible Recipients of Lung Allografts (CAG-00324R2)

  • Sponsor: Center for Medicare and Medicaid Services and Therakos    
  • Principal Investigator: Selim Arcasoy

Consortium Outcomes Studies

Cystic Fibrosis Lung Transplant Transition Learning and Leadership Collaborative 2

  • Sponsor: Cystic Fibrosis Foundation
  • Principal Investigator: Selim Arcasoy

Cystic Fibrosis Lung Transplant Consortium

  • Sponsor: Cystic Fibrosis Foundation
  • Principal Investigator: Luke Benvenuto

Long Term Follow up of the Lung Transplant Outcomes (LTOG) Cohort

  • Sponsor: NHLBI, 5R01HL-134851-04.
  • Primary Center UPENN 
  • Principal Investigator: Luke Benvenuto

Frailty and Patient-Centered Outcomes in Candidates for Lung Transplantation

  • Sponsor: NHLBI, RU01HL145435-02.
  • Primary Center: UCSF
  • Principal Investigator: Luke Benvenuto

Collaboration With CCTI To Study Immune Tolerance and Immune Tracking Following Lung Transplantation