Our research uses molecular genetic and biologic methods to identify genes critical for hearing. We are investigating virally mediated gene therapy to regenerate spiral (cochlear) ganglia—cells that transport sound from the cochlea to the brain—to enable hearing in children born with genetic hearing loss. Our scientists are also studying age-related hearing loss to improve quality of life and reduce associated conditions, such as social isolation, depression, and dementia.

Current Studies

Research on Ketamine for Tinnitus (Ringing in the Ears)

PrincipaI Investigator: Diana Martinez, MD

This research study is investigating ketamine as a possible treatment for tinnitus or ringing in the ears. Ketamine is FDA approved for anesthesia and depression that doesn't respond to regular antidepressants. It is not approved for tinnitus. This study involves two scans using magnetic resonance imaging (MRI). Each of the scans last one and a half hours. Ketamine is administered during one of the scans. The study also involves three audiological appointments, each lasting one hour, to measure tinnitus symptoms.

Faculty Active in Otology Research

The following faculty members are actively conducting research in otology.