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- Commonly present in all ages on fundus photograph.
- The incidence and prevalence of hard drusen is not age related.
- Their presence alone is not sufficient to diagnose early age related maculopathy.
- Hard drusen is not associated with increased risk for the development of choroidal neovascularization.
- Histologically are globular deposits of hyaline material.
- Symptoms: typically asymptomatic
- Small, hard drusen has been defined as being < 64 µm in diameter
- Discrete, yellow-white deposits that are external to RPE
- Almost always have distinct and well-defined border
- Fluorescein angiogram usually demonstrates pin-point window defect.