Thiel-Behnke Dystrophy
  • An unusual subepithelial dystrophy transmitted as an autosomal dominant trait, also called Honeycomb Dystrophy and classified as a variant of Reis-Bucklers'.

Clinical Features

  • Presents in childhood.
  • Symptoms: may present with recurrent painful erosions and decreased vision
  • Signs
    • Often difficult to differentiate Honeycomb from Reis-Bucklers dystrophy, however in the former; the corneal surface is smooth, corneal sensation is normal
    • Typical honeycomb opacity in the corneal subepithelium region develops in the second decade of life


  • Superficial corneal debridement
  • Photo therapeutic keratectomy maybe required in patient with severe recurrent erosions or reduced visual function.