Meesmann's Dystrophy
  • Autosomal dominantly inherited and also called juvenile hereditary epithelial dystrophy.

Clinical Features

  • Symptoms:
    • Foreign body sensation due to epithelial erosion may occur as the cysts begin to rupture onto the ocular surface
    • Decreased visual acuity is usually minimal
  • Signs:
    • Myriads of tiny intraepithelial cysts that are most prominently seen in the interpalpebral zone
    • Slowly progressive rare condition
    • Bilateral, symmetric and may develops in the first 1 or 2 years of life


  • Superficial corneal debridement
  • Photo therapeutic keratectomy maybe required in patient with severe recurrent erosions or reduced visual function.