Anterior Basement Membrane
- Dominantly inherited, also called Map-Dot-Fingerprint Dystrophy or Cogan's microcystic epithelial dystrophy.
- The most common anterior dystrophy incidentally seen in the ophthalmology practice during routine examination.
- Symptoms: more commonly asymptomatic.
- Bilateral, map-like patterns, fingerprint lines, fine dots (microcysts) or comma-shaped opacities
- After the third decade of life, about 10% of patients present with recurrent corneal erosions
- A mild decrease in visual acuity
- Symptomatic relief by instillation of hypertonic NaCl ointment at bedtime.
- Mechanical debridement of the involved corneal epithelium and basement membrane.
- Anterior stromal micropuncture.
- Phototherapeutic keratectomy may be done in severe case, so that more normally adherent epithelium may replace the dystrophic epithelial-basement membrane.