Cryo-EM Publications

Data generated by the Cryo Electron Microscopy Center have been published in a number of high-impact studies. Some recent highlights:

The structure of human sweetness.

  • Authors: Juen Z, Lu Z, Yu R, Chang AN, Wang B, Fitzpatrick AWP, Zuker CS

Structural and molecular basis of choline uptake into the brain by FLVCR2.

  • Authors: Cater RJ, Mukherjee D, Gil-Iturbe E, Erramilli SK, Chen T, Koo K, Santander N, Reckers A, Kloss B, Gawda T, Choy BC, Zhang Z, Katewa A, Larpthaveesarp A, Huang EJ, Mooney SWJ, Clarke OB, Yee SW, Giacomini KM, Kossiakoff AA, Quick M, Arnold T, Mancia F.

Kainate receptor channel opening and gating mechanism.

  • Authors: Gangwar SP, Yelshanskaya MV, Nadezhdin KD, Yen LY, Newton TP, Aktolun M, Kurnikova MG, Sobolevsky AI. Nature. 2024 Jun;630(8017):762-768.

The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.

  • Authors: Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M, Chen B, Grassucci RA, Ehrenberg M, Frank J.

Structure and activity of lipid bilayer within a membrane-protein transporter.

Three-Dimensional Analysis of Mitochondrial Crista Ultrastructure in a Patient with Leigh Syndrome by In Situ Cryoelectron Tomography.

  • Authors: Siegmund SE, Grassucci R, Carter SD, Barca E, Farino ZJ, Juanola-Falgarona M, Zhang P, Tanji K, Hirano M, Schon EA, Frank J, Freyberg Z.

Opening of the human epithelial calcium channel TRPV6.

  • Authors: McGoldrick LL, Singh AK, Saotome K, Yelshanskaya MV, Twomey EC, Grassucci RA, Sobolevsky AI.
Cryo-EM images of TPRV6

Cryo-EM in the News

View recent articles featuring cryo electron microscopy in the CUIMC news room.


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