Vitreous Amyloidosis

• Maybe an isolated finding or as a part of systemic amyloidosis.
• Can be hereditary such as in Familial Amyloidotic Polyneuropathy or nonhereditary.

Clinical Features

• Symptoms: slowly progressive bilateral or unilateral decreased in visual acuity.
• Signs:
  • Unilateral or bilateral typical "glass-wool" or "cobweb" appearance of vitreous opacities
  • Hazy view of the fundus

Management

• Therapeutic vitrectomy in visually significant cases.