Benign pigmented fundus lesions that commonly discovered during routine eye examination.
Clinical Features
Usually asymptomatic.
Signs:
Well-demarcated, round, solitary or multiple gray-brown or black lesions which have flat or scalloped margins.
May be encircled by hyper- or hypo-pigmented halo.
Depigmented or hypopigmented punched-out lacunae or fenestration lesions may be evident within larger lesions.
Multiple areas of grouped CHRPE simulating the animal foot-print are also called "bear tracks".
Generally located in the peripheral but may occasionally in the peripapillary region.
Fluorescein angiography demonstrates blocked choroidal fluorescence by the hypertrophied RPE and no leakage of dye.
Differential diagnosis include: choroidal melanomas, choroidal nevi, melanocytomas of the choroids, hyperplasia of the RPE, post-hemorrhage hemosiderin deposits.
Known to be associated with other systemic findings such as familial adenomatous polyposis and Gardner's syndrome (intestinal polyposis, hamartoma of the skeleton, and multiple soft tissue tumors).