Morning Glory Anomaly

• Rare case and usually unilateral.
• Affects women more than men with a ratio of 2:1.

Clinical Features

• Symptoms: poor vision, amblyopia and strabismus.
• Signs:
  • Leukokoria in the first months or years of life
  • Funnel-shaped, excavation of the optic disc and peripapillary retina
  • Enlarged disc with indistinct border surrounded by depigmented areas
  • White, elevated, hyperplastic glial tissues occupies the central disc
  • Abnormally narrow, straight vessels radiated from the disc margins
• Increased risk of non-rhegmatogenous serous retinal detachment.
• May be associated with basal encephalocele in patients with mid-line facial defect.