Core Facilities by Category

Columbia's core facilities provide investigators with shared access to technically specialized, high-end instrumentation and services. Although these facilities are housed within specific departments or centers, they are accessible to all Columbia faculty, staff, and students.

Commonly requested facilities are grouped by category below. For a full listing of facilities, you can search for shared research facilities on our website.


New Facilities and Resources

New core facilities and services are often developed in response to new scientific needs. Resources that have been added over the past year have been added to a separate listing to help publicize the research tools that are available.


Animal Models

Genetically Modified Mouse Models (Core Facility)

Comparative Pathology/Diagnostic Laboratory (Core Facility)

Humanized Mouse (Limited Access)

Mouse Neurobehavior (Core Facility)

Oncology Precision Therapeutics and Imaging (Core Facility)

Small Animal Radiation Research Platform (Core Facility)


Biorepositories and Assays

Biomarkers at HICCC (Core Facility)

Biomarkers at CTSA (Core Facility)

Center for Advanced Laboratory Medicine (Core Facility)

NY Brain Bank

Tumor Bank (Molecular Pathology Core Facility)

Additional Resources:


Flow Cytometry/FACS

HICCC/CCTI: Black Building, Irving Cancer Research Center locations (Core Facility)

Stem Cell Initiative: Black Building location (Core Facility)

Microbiology & Immunology: HHSC Location

Additional Resources



Histology Service in Molecular Pathology (Core Facility)

  • Routine and specialized histology services including grossing, embedding, tissue processing, sectioning
  • Routine H&E or specialized staining
  • Frozen and FFPE tissue
  • Experimental immunohistochemistry/ immunofluorescence service

Digital and Computational Pathology Laboratory (Core Facility)

  • Acquisition of high resolution images of tissue slides using bright field and fluorescence scanners

Vectra platform at Human Immune Monitoring (Core Facility)

  • Quantitative multiplex immunofluorescent tissue imaging


Imaging and Microscopy

Color enhanced microscopic cellular scan

Confocal and Specialized Microscopy (Core Facility)

Cryogenic Electron Microscopy (Core Facility)

In vivo Imaging (Limited Access)

Additional Resources



Core Facility



Magnetic Resonance Imaging (CUIMC Core Facility)

Magnetic Resonance Imaging (ZMBBI Core Facility)

Positron Emission Tomography (Core Facility)


Proteomics and Metabolomics

Proteomics at HICCC (Core Facility)

Targeted Metabolomics and Lipidomics at CTSA Biomarkers (Core Facility)

Mass Spectrometry, including Mass Spec Imaging, at Morningside (Core Facility)



Image of liquid handling robot

Next-Generation Sequencing (Core Facility)

Single-cell Analysis (Core Facility)

Additional Resources:


Stem Cells

Stem Cell Core (Core Facility)

Mouse embryonic stem (ES) derivation service at Genetically Modified Mouse Models (Core Facility)