- Congenital lesion, characterized by absence of normal retina, RPE and choroid.
- Symptoms: depend on the location of the coloboma and ocular structures involved.
- Typically located in inferotemporal area
- Can be unilateral or bilateral
- May extend and involve the macula
- Maybe associate with coloboma of other ocular structures along the embryonic fissure i.e. optic nerve, iris or lid
- Choroidal neovascularization may develop at the margin of the coloboma
- Associated with higher incidence of retina detachment.
Surgical retinal reattachment procedures include scleral buckling, vitrectomy and silicone oil tamponade.