Iris Coloboma

Iris coloboma with a bridging iris tissue

Clinical Features


  • Maybe asymptomatic
  • Blurry vision
  • Glare


  • Typically located inferonasally
  • Appears as notches in iris or "keyhole pupils"
  • May or may not be associated with chorioretinal coloboma
  • Absence of zonules in the area of a ciliary body coloboma results in lens notching (coloboma)

Other associated syndromes may include:

  • Autosomal dominant uveal coloboma
  • Cat eye syndrome
  • Edwards' syndrome
  • Patau's syndrome
  • Linear nevus sebaceous syndrome. 


  • Supportive with sunglasses, tinted contact lens or contact lens with artificial pupil
  • Surgical iridoplasty in patients with severe and intolerable symptoms