Institute for Cancer Genetics

Recent Publications

  1. Revisiting PARP2 and PARP1 trapping through quantitative live-cell imaging
    Zhang H, Lin X, Zha S
    Biochem Soc Trans. 2022.
     
  2. Glioblastoma hijacks neuronal mechanisms for brain invasion
    Venkataramani V, Yang Y, Schubert MC, Reyhan E, Tetzlaff SK, Wißmann N, Botz M, Soyka SJ, Beretta CA, Pramatarov RL, Fankhauser L, Garofano L, Freudenberg A, Wagner J, Tanev DI, Ratliff M, Xie R, Kessler T, Hoffmann DC, Hai L, Dörflinger Y, Hoppe S, Yabo YA, Golebiewska A, Niclou SP, Sahm F, Lasorella A, Slowik M, Döring L, Iavarone A, Wick W, Kuner T, Winkler F
    Cell. 2022.
     
  3. Targeting Scaffolding Functions of Enzymes Using PROTAC Approaches
    Kim C, Wang XD, Liu Z, Zha S, Yu Y
    Biochemistry. 2022.
     
  4. Rad53 arrests leading and lagging strand DNA synthesis via distinct mechanisms in response to DNA replication stress
    He R, Zhang Z
    Bioessays. 2022.
     
  5. m6A RNA modifications: Key regulators of normal and malignant hematopoiesis
    Sommerkamp P, Brown JA, Haltalli MLR, Mercier FE, Vu LP, Kranc KR
    Exp Hematol. 2022.
     
  6. Super-enhancer hypermutation alters oncogene expression in B cell lymphoma
    Bal E, Kumar R, Hadigol M, Holmes AB, Hilton LK, Loh JW, Dreval K, Wong JCH, Vlasevska S, Corinaldesi C, Soni RK, Basso K, Morin RD, Khiabanian H, Pasqualucci L, Dalla-Favera R
    Nature. 2022.
     
  7. Publisher Correction: Stable inheritance of H3.3-containing nucleosomes during mitotic cell divisions
    Xu X, Duan S, Hua X, Li Z, He R, Zhang Z
    Nat Commun. 2022.
     
  8. Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
    He D, Feng H, Sundberg B, Yang J, Powers J, Christian AH, Wilkinson JE, Monnin C, Avizonis D, Thomas CJ, Friedman RA, Kluger MD, Hollingsworth MA, Grandgenett PM, Klute KA, Toste FD, Chang CJ, Chio IIC
    Mol Cell. 2022.
     
  9. Functional mapping of PHF6 complexes in chromatin remodeling, replication dynamics, and DNA repair
    Alvarez S, da Silva Almeida AC, Albero R, Biswas M, Barreto-Galvez A, Gunning TS, Shaikh A, Aparicio T, Wendorff A, Piovan E, Van Vlierberghe P, Gygi S, Gautier J, Madireddy A, A Ferrando A
    Blood. 2022.
     
  10. Glioma progression is shaped by genetic evolution and microenvironment interactions
    Varn FS, Johnson KC, Martinek J, Huse JT, Nasrallah MP, Wesseling P, Cooper LAD, Malta TM, Wade TE, Sabedot TS, Brat D, Gould PV, Wöehrer A, Aldape K, Ismail A, Sivajothi SK, Barthel FP, Kim H, Kocakavuk E, Ahmed N, White K, Datta I, Moon HE, Pollock S, Goldfarb C, Lee GH, Garofano L, Anderson KJ, Nehar-Belaid D, Barnholtz-Sloan JS, Bakas S, Byrne AT, D'Angelo F, Gan HK, Khasraw M, Migliozzi S, Ormond DR, Paek SH, Van Meir EG, Walenkamp AME, Watts C, Weiss T, Weller M, Palucka K, Stead LF, Poisson LM, Noushmehr H, Iavarone A, Verhaak RGW
    Cell. 2022.
     
  11. Stable inheritance of H3.3-containing nucleosomes during mitotic cell divisions
    Xu X, Duan S, Hua X, Li Z, He R, Zhang Z
    Nat Commun. 2022.
     
  12. H3K4me3 recognition by the COMPASS complex facilitates the restoration of this histone mark following DNA replication
    Serra-Cardona A, Duan S, Yu C, Zhang Z
    Sci Adv. 2022.
     
  13. p53 in ferroptosis regulation: the new weapon for the old guardian
    Liu Y, Gu W
    Cell Death Differ. 2022.
     
  14. Lrwd1 impacts cell proliferation and the silencing of repetitive DNA elements
    Kang TZE, Wan YCE, Zhang Z, Chan KM
    Genesis. 2022.
     
  15. Deciphering the acetylation code of p53 in transcription regulation and tumor suppression
    Xia Z, Kon N, Gu AP, Tavana O, Gu W
    Oncogene. 2022.
     
  16. Mutation in SF3B1 gene promotes formation of polyploid giant cells in Leukemia cells
    Mukherjee S, Ali AM, Murty VV, Raza A
    Med Oncol. 2022.
     
  17. PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites
    Lin X, Jiang W, Rudolph J, Lee BJ, Luger K, Zha S
    Nucleic Acids Res. 2022.
     
  18. Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL
    Antoszewski M, Fournier N, Ruiz Buendía GA, Lourenco J, Liu Y, Sugrue T, Dubey C, Nkosi M, Pritchard CEJ, Huijbers IJ, Segat GC, Alonso-Moreno S, Serracanta E, Belver L, Ferrando AA, Ciriello G, Weng AP, Koch U, Radtke F
    Blood. 2022.
     
  19. Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma
    Cortes JR, Filip I, Albero R, Patiño-Galindo JA, Quinn SA, Lin WW, Laurent AP, Shih BB, Brown JA, Cooke AJ, Mackey A, Einson J, Zairis S, Rivas-Delgado A, Laginestra MA, Pileri S, Campo E, Bhagat G, Ferrando AA, Rabadan R, Palomero T
    Cell Rep. 2022.
     
  20. Regulated interaction of ID2 with the anaphase-promoting complex links progression through mitosis with reactivation of cell-type-specific transcription
    Lee SB, Garofano L, Ko A, D'Angelo F, Frangaj B, Sommer D, Gan Q, Kim K, Cardozo T, Iavarone A, Lasorella A
    Nat Commun. 2022.
     

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