Institute for Cancer Genetics

Recent Publications

  1. DNA-PKcs kinase activity orchestrates both end-processing and end-ligation
    Menolfi D, and Zha S.
    Trends Cell Biol. 2022.
  2. p53 in ferroptosis regulation: the new weapon for the old guardian
    Liu Y, and Gu W.
    Cell Death Differ. 2022.
  3. Targeting S100A9-ALDH1A1-retinoic acid signaling to suppress brain relapse in EGFR-mutant lung cancer
    Biswas AK, Han S, Tai Y, Ma W, Coker C, Quinn SA, Shakri AR, Zhong TJ, Scholze H, Lagos GG, Mela A, Manova-Todorova K, de Stanchina E, Ferrando AA, Mendelsohn C, Canoll P, Yu HA, Paik PK, Saqi A, Shu CA, Kris MG, Massague J, and Acharyya S.
    Cancer Discov. 2022.
  4. Author Correction: Efficient and strand-specific profiling of replicating chromatin with enrichment and sequencing of protein-associated nascent DNA in mammalian cells
    Li Z, Hua X, Serra-Cardona A, Xu X, and Zhang Z.
    Nat Protoc. 2021.
  5. Jak-STAT Inhibition Mediates Romidepsin and Mechlorethamine Synergism in Cutaneous T-Cell Lymphoma
    Cortes JR, Patrone CC, Quinn SA, Gu Y, Sanchez-Martin M, Mackey A, Cooke AJ, Shih BB, Laurent AP, Trager MH, Ferrando AA, Geskin LJ, and Palomero T.
    J Invest Dermatol. 2021.
  6. Targeting BRCA-mutated tumors in mitosis
    Menolfi D, and Zha S.
    Nat Cancer. 2021.
  7. Epigenetic Rewiring of BCR Signaling as a Novel Mechanism of Ibrutinib Resistance in ABC-DLBCL
    and Pasqualucci L.
    Blood Cancer Discov. 2021.
  8. An unexpected role for Dicer as a reader of the unacetylated DNA binding domain of p53 in transcriptional regulation
    Yang X, Wang X, Li Z, Duan S, Li H, Jin J, Zhang Z, and Gu W.
    Sci Adv. 2021.
  9. Intracellular cholesterol pools regulate oncogenic signaling and epigenetic circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia
    Rashkovan M, Albero R, Gianni F, Perez-Duran P, Miller HI, Mackey AL, Paietta EM, Tallman MS, Rowe JM, Litzow MR, Wiernik PH, Luger S, Sulis ML, Soni RK, and Ferrando AA.
    Cancer Discov. 2021.
  10. Inhibition of ERK/MAPK signaling as potential therapy to prevent optic pathway glioma in infants with neurofibromatosis type 1
    D'Angelo F, and Lasorella A.
    Dev Cell. 2021.
  11. A mechanism for Rad53 to couple leading- and lagging-strand DNA synthesis under replication stress in budding yeast
    Serra-Cardona A, Yu C, Zhang X, Hua X, Yao Y, Zhou J, Gan H, and Zhang Z.
    Proc Natl Acad Sci USA. 2021.
  12. DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice
    Wang XS, Menolfi D, Wu-Baer F, Fangazio M, Meyer SN, Shao Z, Wang Y, Zhu Y, Lee BJ, Estes VM, Cupo OM, Gautier J, Pasqualucci L, Dalla-Favera R, Baer R, and Zha S.
    Proc Natl Acad Sci USA. 2021.
  13. Genetics of Chronic Lymphocytic Leukemia
    Bosch F, and Dalla-Favera R.
    Cancer J. 2021.
  14. The making of the glioblastoma classification
    Lasorella A, and Iavarone A.
    Br J Cancer. 2021.
  15. iPLA2β-mediated lipid detoxification controls p53-driven ferroptosis independent of GPX4
    Chen D, Chu B, Yang X, Liu Z, Jin Y, Kon N, Rabadan R, Jiang X, Stockwell BR, and Gu W.
    Nat Commun. 2021.
  16. Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma
    Fangazio M, Ladewig E, Gomez K, Garcia-Ibanez L, Kumar R, Teruya-Feldstein J, Rossi D, Filip I, Pan-Hammarström Q, Inghirami G, Boldorini R, Ott G, Staiger AM, Chapuy B, Gaidano G, Bhagat G, Basso K, Rabadan R, Pasqualucci L, and Dalla-Favera R.
    Proc Natl Acad Sci USA. 2021.
  17. Biology of Germinal Center B Cells Relating to Lymphomagenesis
    and Basso K.
    Hemasphere. 2021.
  18. Inhibition of DNA replication initiation by silver nanoclusters
    Tao Y, Aparicio T, Li M, Leong KW, Zha S, and Gautier J.
    Nucleic Acids Res. 2021.
  19. Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker
    Chen AX, Gartrell RD, Zhao J, Upadhyayula PS, Zhao W, Yuan J, Minns HE, Dovas A, Bruce JN, Lasorella A, Iavarone A, Canoll P, Sims PA, and Rabadan R.
    Genome Med. 2021.
  20. Biology and Molecular Pathogenesis of Mature T-Cell Lymphomas
    Cortés JR, and Palomero T.
    Cold Spring Harb Perspect Med. 2021.

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