Institute for Cancer Genetics

Recent Publications

  1. Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma
    Fangazio M, Ladewig E, Gomez K, Garcia-Ibanez L, Kumar R, Teruya-Feldstein J, Rossi D, Filip I, Pan-Hammarström Q, Inghirami G, Boldorini R, Ott G, Staiger AM, Chapuy B, Gaidano G, Bhagat G, Basso K, Rabadan R, Pasqualucci L, and Dalla-Favera R.
    Proc Natl Acad Sci USA. 2021.
  2. Inhibition of DNA replication initiation by silver nanoclusters
    Tao Y, Aparicio T, Li M, Leong KW, Zha S, and Gautier J.
    Nucleic Acids Res. 2021.
  3. Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker
    Chen AX, Gartrell RD, Zhao J, Upadhyayula PS, Zhao W, Yuan J, Minns HE, Dovas A, Bruce JN, Lasorella A, Iavarone A, Canoll P, Sims PA, and Rabadan R.
    Genome Med. 2021.
  4. Biology and Molecular Pathogenesis of Mature T-Cell Lymphomas
    Cortés JR, and Palomero T.
    Cold Spring Harb Perspect Med. 2021.
  5. Deregulation of enhancer structure, function, and dynamics in acute lymphoblastic leukemia
    Belver L, Albero R, and Ferrando AA.
    Trends Immunol. 2021.
  6. Efficient and strand-specific profiling of replicating chromatin with enrichment and sequencing of protein-associated nascent DNA in mammalian cells
    Li Z, Hua X, Serra-Cardona A, Xu X, and Zhang Z.
    Nat Protoc. 2021.
  7. Mouse Models in the Study of Mature B-Cell Malignancies
    Pasqualucci L, and Klein U.
    Cold Spring Harb Perspect Med. 2021.
  8. The complexity of p53-mediated metabolic regulation in tumor suppression
    Liu Y, and Gu W.
    Semin Cancer Biol. 2021.
  9. The making of the glioblastoma classification
    Lasorella A, and Iavarone A.
    Br J Cancer. 2021.
  10. FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis
    Milanovic M, Shao Z, Estes VM, Wang XS, Menolfi D, Lin X, Lee BJ, Xu J, Cupo OM, Wang D, and Zha S.
    J Immunol. 2021.
  11. The plié by DNA-PK: dancing on DNA
    Zha S, Shao Z, and Zhu Y.
    Mol Cell. 2021.
  12. Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function
    Kon N, Churchill M, Li H, Mukherjee S, Manfredi JJ, and Gu W.
    Cancer Res. 2021.
  13. The UVSSA complex alleviates MYC-driven transcription stress
    Sato M, Liebau AW, Liu Z, Liu L, Rabadan R, and Gautier J.
    J Cell Biol. 2021.
  14. PDA Got SERious Nerves
    Yang X, and Chio IIC.
    Trends Cancer. 2021.
  15. Pathway-based classification of glioblastoma uncovers a mitochondrial subtype with therapeutic vulnerabilities
    Garofano L, Migliozzi S, Oh YT, D'Angelo F, Najac RD, Ko A, Frangaj B, Caruso FP, Yu K, Yuan J, Zhao W, Di Stefano AL, Bielle F, Jiang T, Sims P, Suvà ML, Tang F, Su XD, Ceccarelli M, Sanson M, Lasorella A, and Iavarone A.
    Nat Cancer. 2021.
  16. The Cancer-Associated ATM R3008H Mutation Reveals the Link between ATM Activation and Its Exchange
    Milanovic M, Houghton LM, Menolfi D, Lee JH, Yamamoto K, Li Y, Lee BJ, Xu J, Estes VM, Wang D, Mckinnon PJ, Paull TT, and Zha S.
    Cancer Res. 2021.
  17. mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression
    Kon N, Ou Y, Wang SJ, Li H, Rustgi AK, and Gu W.
    Genes Dev. 2021.
  18. FYN-TRAF3IP2 induces NF-κB signaling-driven peripheral T cell lymphoma
    Moon CS, Reglero C, Cortes JR, Quinn SA, Alvarez S, Zhao J, Lin WW, Cooke AJ, Abate F, Soderquist CR, Fiñana C, Inghirami G, Campo E, Bhagat G, Rabadan R, Palomero T, and Ferrando AA.
    Nat Cancer. 2021.
  19. DNA Damage Response in Xenopus laevis Cell-Free Extracts
    Aparicio Casado T, and Gautier J.
    Methods Mol Biol. 2021.
  20. p53 activation vs. stabilization: an acetylation tale from the C-terminal tail
    Kon N, and Gu W.
    Oncoscience. 2021.

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