Recent Publications

1. Tryptophan Metabolism Acts as a New Anti-Ferroptotic Pathway to Mediate Tumor Growth
   Liu D, Liang CH, Huang B, Zhuang X, Cui W, Yang L, Yang Y, Zhang Y, Fu X, Zhang X, Du L, Gu W, Wang X, Yin C, Chai R, Chu B
   Adv Sci (Weinh). 2023.
    
2. Double-strand break repair and mis-repair in 3D
   Zagelbaum J, Gautier J
   DNA Repair (Amst). 2023.
    
3. Multiscale reorganization of the genome following DNA damage facilitates chromosome translocations via nuclear actin polymerization
   Zagelbaum J, Schooley A, Zhao J, Schrank BR, Callen E, Zha S, Gottesman ME, Nussenzweig A, Rabadan R, Dekker J, Gautier J
   Nat Struct Mol Biol. 2022.
    
4. Epigenome Programming by H3.3K27M Mutation Creates a Dependence of Pediatric Glioma on SMARCA4
   Mo Y, Duan S, Zhang X, Hua X, Zhou H, Wei HJ, Watanabe J, McQuillan N, Su Z, Gu W, Wu CC, Vakoc CR, Hashizume R, Chang K, Zhang Z
   Cancer Discov. 2022.
    
5. Canopy Homolog 2 contributes to liver oncogenesis by promoting unfolded protein response-dependent destabilization of tumor protein P53
   Hong F, Lin CY, Yan J, Dong Y, Ouyang Y, Kim D, Zhang X, Liu B, Sun S, Gu W, Li Z
   Hepatology. 2022.
    
6. Genomic profiling for clinical decision making in lymphoid neoplasms
   de Leval L, Alizadeh AA, Bergsagel PL, Campo E, Davies A, Dogan A, Fitzgibbon J, Horwitz SM, Melnick AM, Morice WG, Morin RD, Nadel B, Pileri SA, Rosenquist R, Rossi D, Salaverria I, Steidl C, Treon SP, Zelenetz AD, Advani RH, Allen CE, Ansell SM, Chan WC, Cook JR, Cook LB, d'Amore F, Dirnhofer S, Dreyling M, Dunleavy K, Feldman AL, Fend F, Gaulard P, Ghia P, Gribben JG, Hermine O, Hodson DJ, Hsi ED, Inghirami G, Jaffe ES, Karube K, Kataoka K, Klapper W, Kim WS, King RL, Ko YH, LaCasce AS, Lenz G, Martin-Subero JI, Piris MA, Pittaluga S, Pasqualucci L, Quintanilla-Martinez L, Rodig SJ, Rosenwald A, Salles GA, San-Miguel J, Savage KJ, Sehn LH, Semenzato G, Staudt LM, Swerdlow SH, Tam CS, Trotman J, Vose JM, Weigert O, Wilson WH, Winter JN, Wu CJ, Zinzani PL, Zucca E, Bagg A, Scott DW
   Blood. 2022.
    
7. Mcm2 promotes stem cell differentiation via its ability to bind H3-H4
   Xu X, Hua X, Brown K, Ren X, Zhang Z
   Elife. 2022.
    
8. Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia
   Reglero C, Dieck CL, Zask A, Forouhar F, Laurent AP, Lin WW, Albero R, Miller HI, Ma C, Gastier-Foster JM, Loh ML, Tong L, Stockwell BR, Palomero T, Ferrando AA
   Cancer Discov. 2022.
    
9. Author Correction: Super-enhancer hypermutation alters oncogene expression in B cell lymphoma
   Bal E, Kumar R, Hadigol M, Holmes AB, Hilton LK, Loh JW, Dreval K, Wong JCH, Vlasevska S, Corinaldesi C, Soni RK, Basso K, Morin RD, Khiabanian H, Pasqualucci L, Dalla-Favera R
   Nature. 2022.
    
10. Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
    Li Y, Goldberg EM, Chen X, Xu X, McGuire JT, Leuzzi G, Karagiannis D, Tate T, Farhangdoost N, Horth C, Dai E, Li Z, Zhang Z, Izar B, Que J, Ciccia A, Majewski J, Yoon AJ, Ailles L, Mendelsohn CL, Lu C
    Mol Cell. 2022.
     
11. A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma
    Zhou RW, Xu J, Martin TC, Zachem AL, He J, Ozturk S, Demircioglu D, Bansal A, Trotta AP, Giotti B, Gryder B, Shen Y, Wu X, Carcamo S, Bosch K, Hopkins B, Tsankov A, Steinhagen R, Jones DR, Asara J, Chipuk JE, Brody R, Itzkowitz S, Chio IIC, Hasson D, Bernstein E, Parsons RE
    Nat Commun. 2022.
     
12. Dual-Modulated Release of a Cytotoxic Photosensitizer Using Photogenerated Reactive Oxygen Species and Glutathione
    Lee CG, Lee C, Lee J, Nam JS, Kim BS, Kwon TH
    Angew Chem Int Ed Engl. 2022.
     
13. Phase I trial of the TNF-α inhibitor certolizumab plus chemotherapy in stage IV lung adenocarcinomas
    Paik PK, Luo J, Ai N, Kim R, Ahn L, Biswas A, Coker C, Ma W, Wong P, Buonocore DJ, Lai WV, Chaft JE, Acharyya S, Massagué J, Kris MG
    Nat Commun. 2022.
     
14. NF-κB Mutations in Germinal Center B-Cell Lymphomas: Relation to NF-κB Function in Normal B Cells
    Pasqualucci L, Klein U
    Biomedicines. 2022.
     
15. The complexity of p53-mediated metabolic regulation in tumor suppression
    Liu Y, Gu W
    Semin Cancer Biol. 2022.
     
16. The Prostacyclin Analogue Iloprost Modulates CXCL10 in Systemic Sclerosis
    Colasanti T, Stefanantoni K, Fantini C, Corinaldesi C, Vasile M, Marampon F, Di Luigi L, Antinozzi C, Sgrò P, Lenzi A, Riccieri V, Crescioli C
    Int J Mol Sci. 2022.
     
17. Rad53 arrests leading and lagging strand DNA synthesis via distinct mechanisms in response to DNA replication stress
    He R, Zhang Z
    Bioessays. 2022.
     
18. Revisiting PARP2 and PARP1 trapping through quantitative live-cell imaging
    Zhang H, Lin X, Zha S
    Biochem Soc Trans. 2022.
     
19. Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
    He D, Feng H, Sundberg B, Yang J, Powers J, Christian AH, Wilkinson JE, Monnin C, Avizonis D, Thomas CJ, Friedman RA, Kluger MD, Hollingsworth MA, Grandgenett PM, Klute KA, Toste FD, Chang CJ, Chio IIC
    Mol Cell. 2022.
     
20. Tissue-specific modifier alleles determine Mertk loss-of-function traits
    Akalu YT, Mercau ME, Ansems M, Hughes LD, Nevin J, Alberto EJ, Liu XN, He LZ, Alvarado D, Keler T, Kong Y, Philbrick WM, Bosenberg M, Finnemann SC, Iavarone A, Lasorella A, Rothlin CV, Ghosh S
    Elife. 2022.
     

Updated on 01/12/2023.