Tezel G. Molecular regulation of neuroinflammation in glaucoma: Current knowledge and the ongoing search for new treatment targets. Prog Retin Eye Res. 2022;87:100998. PMID: 34348167
Yang X, Zeng Q, Tezel G. Regulation of distinct caspase-8 functions in retinal ganglion cells and astroglia in experimental glaucoma. Neurobiol Dis. 2021;150:105258. PMID: 33434617
Aydin R, Baris M, Engin CD, Al-Aswad L, Blumberg DM, Cioffi GA, Liebmann JM, Tezel TH, Tezel G. Early localized alterations of the retinal inner plexiform layer in association with visual field worsening in glaucoma patients. PLOS ONE. 2021;16:e0247401. PMID: 33630899
Tezel G. Multifactorial pathogenic processes of retinal ganglion cell degeneration in glaucoma towards multi-target strategies for broader treatment effects. Special Issue “Retinal Ganglion Cell Neuroprotection: Approaches to the Treatment of Optic Neuropathies”. Cells. 2021;10:1372-1399.PMID: 34199494
Yang X, Zeng Q, Baris M, Tezel G. Transgenic inhibition of astroglial NF-κB restrains the neuroinflammatory and neurodegenerative outcomes of experimental mouse glaucoma. J Neuroinflammation. 2020;17:252. PMID: 32859212
Tezel G. A broad perspective on the molecular regulation of retinal ganglion cell degeneration in glaucoma. Special Issue “Glaucoma: A Neurodegenerative Disease of the Retina and Beyond”. Prog Brain Res. 2020;256:49-77. PMID: 32958215
Yang X, Zeng Q, Goktas E, Gopal K, Al-Aswad L, Blumberg D, Cioffi GA, Liebmann JM, Suh LH, Trief D, Tezel G. T-lymphocyte subset distribution and activity in patients with glaucoma. Invest Ophthalmol Vis Sci. 2019;60:877-888. PMID: 30821813
Hondur G, Göktas E, Yang X, Al-Aswad L, Auran JD, Blumberg DM, Cioffi GA, Liebmann JM, Suh LH, Trief, Tezel G. Oxidative stress-related molecular biomarker candidates for glaucoma. Invest Ophthalmol Vis Sci. 2017;58:4078-4088. PMID: 28820925
Yang X, Hondur G, Tezel G. Antioxidant treatment limits neuroinflammation in glaucoma. Invest Ophthalmol Vis Sci. 2016;57:2344-2354. PMID: 27127934
Yang X, Hondur G, Li M, Cai J, Klein JB, Kuehn MH, Tezel G. Proteomics analysis of molecular risk factors in the ocular hypertensive human retina. Invest Ophthalmol Vis Sci. 2015;56:5816-5830. PMID: 26348630
Tezel G. A decade of the proteomics studies of glaucomatous neurodegeneration. Special Issue “Proteomics and the Eye”. Proteomics Clin Appl. 2014;8:154-167. PMID: 24415558
Tezel G. A proteomics view of the molecular mechanisms and biomarkers of glaucomatous neurodegeneration. Prog Retin Eye Res. 2013;35:18-43. PMID: 23396249
Tezel G, Yang X, Luo C, Cai J, Powell DW. An astrocyte-specific proteomic approach to inflammatory responses in experimental rat glaucoma. Invest Ophthalmol Vis Sci. 2012;53:4220-4233. PMID: 22570341
Tezel G, Thornton IL, Tong MG, Luo C, Yang X, Cai J, Powell DW, Soltau JB, Liebmann JM, Ritch R. Immunoproteomic analysis of potential serum biomarker candidates in human glaucoma. Invest Ophthalmol Vis Sci. 2012;53:8222-8231. PMID: 23150628
Yang X, Luo C, Cai J, Powell DW, Yu D, Kuehn MH, Tezel G. Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina. Invest Ophthalmol Vis Sci. 2011;52:8442-8454. PMID: 21917936
Luo C, Yang X, Kain AD, Powell DW, Kuehn MH, Tezel G. Glaucomatous tissue stress and the regulation of immune response through the toll-like receptor signaling. Invest Ophthalmol Vis Sci. 2010;51:5697-5707. PMID: 20538986
Tezel G, Yang X, Luo C, Kain AD, Powell DW, Kuehn MH, Kaplan HJ. Oxidative stress and the regulation of complement activation in human glaucoma. Invest Ophthalmol Vis Sci. 2010;51:5071-5082. PMID: 20484586
Tezel G, Yang X, Luo C, Cai J, Kain AD, Powell DW, Kuehn MH, Pierce WM. Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation. Invest Ophthalmol Vis Sci. 2008;51:907-919. PMID: 19741249
Yang X, Luo C, Cai J, Pierce WM, Tezel G. Phosphorylation-dependent interaction with 14-3-3 regulates Bad trafficking in retinal ganglion cells. Invest Ophthalmol Vis Sci. 2008;49:2483-2494. PMID: 18296656
Wax MB, Tezel G, Yang J, Peng G, Patil RV, Agarwal N, Sappington RM, Calkins DJ. Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T cell-derived Fas-ligand. J Neurosci. 2008;28:12085-12096. PMID: 19005073
Tezel G. TNF-α signaling in glaucomatous neurodegeneration. Research series: "Glaucoma: An Open-Window to Neurodegeneration and Neuroprotection”. Prog Brain Res. 2008;173:409-421. PMID: 18929124
Tezel G, Yang X, Luo C, Peng Y, Sun SL, Sun D. Mechanisms of immune system activation in glaucoma: Oxidative stress stimulates antigen presentation by the retina and optic nerve head glia. Invest Ophthalmol Vis Sci. 2007;48:705-714. PMID: 17251469
Tezel G, Yang X, Cai J. Proteomic identification of oxidatively modified retinal proteins in a chronic pressure-induced rat model of glaucoma. Invest Ophthalmol Vis Sci. 2005;46:3177-3187. PMID: 16123417
Tezel G, Yang X, Yang J, Wax MB. Role of tumor necrosis factor receptor-1 in the death of retinal ganglion cells following optic nerve crush injury in mice. Brain Res. 2004;996:202-212. PMID: 14697498
Tezel G, Yang X. Caspase-independent component of retinal ganglion cell death, in vitro. Invest Ophthalmol Vis Sci. 2004;45:4049-4059. PMID: 15505055
Tezel G, Hernandez MR, Wax MB. In vitro evaluation of reactive astrocyte migration, a component of tissue remodeling in glaucomatous optic nerve head. Glia. 2001;34:178-189. PMID: 11329180
Tezel G, Wax MB. Increased production of TNF-α by glial cells exposed to simulated ischemia or elevated hydrostatic pressure induces apoptosis in co-cultured retinal ganglion cells. J Neurosci. 2000;20:8693-8700. PMID: 11102475
Tezel G, Wax MB. The mechanisms of hsp27 antibody-mediated apoptosis in retinal cells. J Neurosci. 2000;20:3552-3562. PMID: 10804196
Tezel G, Seigel GM, Wax MB. Autoantibodies to small heat shock proteins in glaucoma. Invest Ophthalmol Vis Sci. 1998;39:2277-2287. PMID: 9804136
