Research Labs

A pair of gloved hands hold a set of frozen vials n a research lab

Explore the research labs of the Columbia Center for Translational Immunology.

  • The Chen Lab utilizes islet transplantation models to explore areas of islet cellular and molecular biology that are pertinent to the development of diabetes.

  • The Creusot Lab’s research interests revolve around the pathogenesis and prevention of Type 1 Diabetes.

  • The Fu Lab is investigating the mechanistic study and strategy development of inducing mixed chimerism in humans after solid organ transplantation to reduce rejection and promote tolerance.

  • The Han Lab's research investigates the function of T cells as they pertain to human diseases, including cancer and autoimmunity.

  • The Mapara Lab's research is focused on developing new approaches to improve the outcome of patients with hematologic malignancies undergoing allogeneic hematopoietic stem cell transplantation.

  • Dr. Maria Mittelbrunn is a visiting Professor at the Center for Translational Immunology (CCTI) and Columbia Center for Human Longevity (CCHL).

  • The Mor Lab's research targets patients suffering from cancer and autoimmune disease and seeks to improve the outcome of their treatment.

  • The Muranski Lab focuses on developing potent T lymphocytes for adoptive immunotherapy of viral infections and cancer.

    cGMP: In-House development of Novel Therapies at CUIMC include Investigator Initiated Trials of virus-specific t cells, Novel T-cell therapies for cancer and point of care CAR-T manufacturing
  • Dr. Nowak’s laboratory is investigating mechanisms of transplant tolerance induction in xenotransplantation.

  • The Reshef Lab investigates lymphocyte trafficking mechanisms that affect anti-tumor and anti-host responses in allogeneic stem-cell transplantation and in cancer immunotherapy.

  • The Sachs laboratory is involved in studies of transplantation biology, with an emphasis on understanding and manipulating transplantation immunity and tolerance.

  • The Sykes Lab's program currently includes major projects in the area of xenograft tolerance induction in humanized mouse models.

    Members of the Sykes Lab pose for a group photo outdoors
  • The Weiner Lab investigates the immunological basis of rejection and tolerance after solid organ transplantation.

  • The Yousefzadeh Lab studies the mechanistic role of senescent cells on aging, in addition to testing interventions to extend healthspan and lifespan.

  • Dr. Zorn’s primary research is on B cell immunity with a focus on innate-like B cells and natural antibodies.