Columbia Center for Translational Immunology (CCTI)

Research Labs

A pair of gloved hands hold a set of frozen vials n a research lab

Explore the research labs of the Columbia Center for Translational Immunology.

  • Chen Lab

    The Chen Lab utilizes islet transplantation models to explore areas of islet cellular and molecular biology that are pertinent to the development of diabetes.

  • Creusot Lab

    The Creusot Lab’s research interests revolve around the pathogenesis, modeling, and immunotherapy of Type 1 diabetes.

  • Fu Lab

    The Fu Lab is investigating the mechanistic study and strategy development of inducing mixed chimerism in humans after solid organ transplantation to reduce rejection and promote tolerance.

  • Han Lab

    The Han Lab's research investigates the function of T cells as they pertain to human diseases, including cancer and autoimmunity.

  • Mapara Lab

    The Mapara Lab's research is focused on developing new approaches to improve the outcome of patients with hematologic malignancies undergoing allogeneic hematopoietic stem cell transplantation.

  • Mittelbrunn Lab

    Dr. Maria Mittelbrunn is a visiting Professor at the Center for Translational Immunology (CCTI) and Columbia Center for Human Longevity (CCHL).

  • Mor Lab

    The Mor Lab's research targets patients suffering from cancer and autoimmune disease and seeks to improve the outcome of their treatment.

  • Muranski Lab

    The Muranski Lab focuses on developing potent T lymphocytes for adoptive immunotherapy of viral infections and cancer.

    cGMP: In-House development of Novel Therapies at CUIMC include Investigator Initiated Trials of virus-specific t cells, Novel T-cell therapies for cancer and point of care CAR-T manufacturing

  • Nowak Lab

    Dr. Nowak’s laboratory is investigating mechanisms of transplant tolerance induction in xenotransplantation.

    Members of the Nowak Lab with Megan Sykes, MD, Director of CCTI

  • Reshef Lab

    The Reshef Lab investigates lymphocyte trafficking mechanisms that affect anti-tumor and anti-host responses in allogeneic stem-cell transplantation and in cancer immunotherapy.

  • Sachs Lab

    The Sachs laboratory is involved in studies of transplantation biology, with an emphasis on understanding and manipulating transplantation immunity and tolerance.

  • Sykes Lab

    The Sykes Lab's program currently includes major projects in the area of xenograft tolerance induction in humanized mouse models.

    Members of the Sykes Lab pose for a group photo outdoors

  • Weiner Lab

    The Weiner Lab investigates the immunological basis of rejection and tolerance after solid organ transplantation.

  • Yousefzadeh Lab

    The Yousefzadeh Lab studies the mechanistic role of senescent cells on aging, in addition to testing interventions to extend healthspan and lifespan.

  • Zorn Lab

    Dr. Zorn’s primary research is on B cell immunity with a focus on innate-like B cells and natural antibodies.