Purnema Madahar, MD, MS

Critical Care Medicine
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Dr. Purnema Madahar is the Assistant Director of the Medical Intensive Care Units and the Medical Critical Care Services at Milstein Hospital, and an Assistant Professor of Medicine at Columbia University Irving Medical Center. She is a pulmonary intensivist, ECMO attending, and active member of the Center for Acute Respiratory Failure research group. Her current clinical research interests include identifying risk factors and associated outcomes in patients with acute respiratory failure and critical illness, clinical outcomes in patients supported with extracorporeal membrane oxygenation (ECMO), and utilization of information technology to improve patient outcomes. Dr. Madahar is actively involved in several hospital-based committees related to improving quality of care for patients in the ICUs. She has been accepted to the NewYork-Presbyterian Leadership Education and Development (LEAD) Academy for the 2022-2023 academic year, a highly competitive program that aims to cultivate physician leaders.

Areas of Expertise / Conditions Treated

  • Acute Respiratory Distress Syndrome (ARDS)
  • Critical Care
  • Extracorporeal Membrane Oxygenation (ECMO)
  • Intensive Care
  • Mechanical Ventilation
  • Pulmonary Critical Care Medicine
  • Pulmonary Disease
  • Respiratory Failure
  • Sepsis

Academic Appointments

  • Assistant Professor of Medicine at CUMC

Administrative Titles

  • Assistant Director, Medical ICUs and Medical Critical Care Services

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center
  • NewYork-Presbyterian Allen Hospital


  • Female

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Credentials & Experience

Education & Training

  • BS, Biology, Neuroscience & Psychology, Brandeis University
  • MS, Patient Oriented Research, Columbia University Mailman School of Public Health
  • MD, State University of New York at Stony Brook School of Medicine
  • Internship: Albert Einstein / Montefiore Medical Center
  • Residency: Albert Einstein / Montefiore Medical Center
  • Residency: Albert Einstein / Montefiore Medical Center, Chief Resident
  • Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center

Board Certifications

  • Internal Medicine
  • Critical Care Medicine
  • Pulmonary Disease

Honors & Awards

  • NewYork-Presbyterian Leadership Education and Development (LEAD) Academy Attending (2022-2023)
  • TL1 Precision Medicine Postdoctoral Research Fellow (2016)
  • Resident Development Scholarship, American Thoracic Society (2012)
  • Intensified Research Track in Internal Medicine Awardee (2011)
  • NIH Intramural Research Training Award (2005)
  • Rishon M. Bialer ’64 Endowed Scholarship (2004)


Research Interests

  • Acute Respiratory Distress Syndrome (ARDS)
  • Acute Respiratory Failure
  • Airway Management
  • Critical Care Outcomes
  • Extracorporeal Membrane Oxygenation (ECMO)
  • Health Technology and Informatics

Selected Publications

  • Dzierba AL, Khalil AM, Derry KL, Madahar P, Beitler JR. Discordance Between Respiratory Drive and Sedation Depth in Critically Ill Patients Receiving Mechanical Ventilation. Crit Care Med. 2021 Jun 9;. doi: 10.1097/CCM.0000000000005113. [Epub ahead of print] PubMed PMID: 34115638.
  • Abrams D, Madahar P, Eckhardt CM, Short B, Yip NH, Parekh M, Serra A, Dubois RL, Saleem D, Agerstrand C, Scala P, Benvenuto L, Arcasoy SM, Sonett JR, Takeda K, Meier A, Beck J, Ryan P, Fan E, Hodgson CL, Bacchetta M, Brodie D. Early Mobilization during ECMO for Cardiopulmonary Failure in Adults: Factors Associated with Intensity of Treatment. Ann Am Thorac Soc. 2021 Jun 2;. doi: 10.1513/AnnalsATS.202102-151OC. [Epub ahead of print] PubMed PMID: 34077700.
  • Madahar P, Talmor D, Beitler JR. Transpulmonary Pressure-guided Ventilation to Attenuate Atelectrauma and Hyperinflation in Acute Lung Injury. Am J Respir Crit Care Med. 2021 Apr 15;203(8):934-937. doi: 10.1164/rccm.202011-4116ED. PubMed PMID: 33227213; PubMed Central PMCID: PMC8048752.
  • Madahar P, Wunsch H, Jha P, Slutsky AS, Brodie D. Trends in COVID-19-related in-hospital mortality: lessons learned from nationwide samples. Lancet Respir Med. 2021 Apr;9(4):322-324. doi: 10.1016/S2213-2600(21)00080-1. Epub 2021 Feb 15. PubMed PMID: 33600776; PubMed Central PMCID: PMC7906680.
  • Agerstrand C, Dubois R, Takeda K, Uriel N, Lemaitre P, Fried J, Masoumi A, Cheung EW, Kaku Y, Witer L, Liou P, Gerall C, Klein-Cloud R, Abrams D, Cunningham J, Madahar P, Parekh M, Short B, Yip NH, Serra A, Beck J, Brewer M, Fung K, Mullin D, Oommen R, Stanifer BP, Middlesworth W, Sonett J, Brodie D. Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019: Crisis Standards of Care. ASAIO J. 2021 Mar 1;67(3):245-249. doi: 10.1097/MAT.0000000000001376. PubMed PMID: 33627596.
  • Madahar P, Beitler JR. Emerging concepts in ventilation-induced lung injury. F1000Res. 2020;9. doi: 10.12688/f1000research.20576.1. eCollection 2020. Review. PubMed PMID: 32269759; PubMed Central PMCID: PMC7111496.
  • Rosenzweig EB, Gannon WD, Madahar P, Agerstrand C, Abrams D, Liou P, Brodie D, Bacchetta M. Extracorporeal life support bridge for pulmonary hypertension: A high-volume single-center experience. J Heart Lung Transplant. 2019 Dec;38(12):1275-1285. doi: 10.1016/j.healun.2019.09.004. Epub 2019 Sep 12. PubMed PMID: 31582284.
  • Dzierba AL, Abrams D, Madahar P, Muir J, Agerstrand C, Brodie D. Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation. J Crit Care. 2019 Oct;53:98-106. doi: 10.1016/j.jcrc.2019.05.014. Epub 2019 May 29. PubMed PMID: 31202165.