Joseph G. Jurcic, MD
Overview
Dr. Joseph Jurcic is Professor of Medicine at Columbia University Medical Center and Director of the Hematologic Malignancies Section of the Division of Hematology/Oncology. His main focus is the treatment of acute and chronic leukemias, myeloproliferative neoplasms, and myelodysplastic syndrome. Research interests include acute myeloid leukemia, radioimmunotherapy with alpha and beta particle-emitting radioisotopes, monoclonal antibody therapy for leukemia, the development of novel small molecule inhibitors for leukemia, and the molecular monitoring of minimal residual disease.
He is the 2001 recipient of the Louis and Allston Boyer Young Investigator Award for Distinguished Achievement in Biomedical Research from Memorial Sloan-Kettering Cancer Center. He is author or coauthor of more than 80 articles and book chapters, has been the principal investigator on over 25 clinical trials, and regularly lectures at national and international meetings. He serves as a Leukemia Section Editor for The Oncologist. Prior to joining the faculty at Columbia University Medical Center, he was an Attending Physician on the Leukemia Service at Memorial Sloan-Kettering Cancer Center for over 18 years.
Areas of Expertise / Conditions Treated
- Acute Leukemia
- Acute Lymphocytic Leukemia
- Acute Myeloid Leukemia
- Aplastic Anemia
- Chronic Leukemia
- Chronic Lymphocytic Leukemia
- Chronic Myelogenous Leukemia
- CMML (Chronic Myelomonocytic Leukemia)
- Essential Thrombocythemia
- Hairy Cell Leukemia
- Hematologic Malignancy
- Hemolytic Anemia
- Immune Thrombocytopenia
- Large Granular Lymphocytic Leukemia
- Leukemia
- Lymphoblastic Leukemia
- Myelodysplastic Syndrome
- Myelofibrosis
- Myeloproliferative Disease
- Polycythemia Vera
- Rare Diseases & Myeloproliferative Neoplasm
Academic Appointments
- Professor of Medicine at CUMC
Administrative Titles
- Director, Hematologic Malignancies Section
Hospital Affiliations
- NewYork-Presbyterian / Columbia University Irving Medical Center
Gender
- Male
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Phone Appointments
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Location(s)
Insurance Accepted
Aetna
- Aetna Signature Administrators
- HMO
- NYP Employee Plan
- NY Signature
- PPO
- Student Health
Affinity Health Plan
- Medicaid Managed Care
AgeWell
- Medicare Managed Care
- Special Needs
Amerigroup of New Jersey
- New Jersey Services (Medicaid Managed Care)
Cigna
- EPO
- Great West (National)
- HMO
- Medicare Managed Care
- POS
- PPO
Emblem/GHI
- Medicare Managed Care
- PPO
Emblem/HIP
- ConnectiCare
- EPO
- Essential Plan
- HMO
- Medicare Managed Care
- POS
- PPO
- Select Care (Exchange)
- Vytra
Empire Blue Cross/Blue Shield
- EPO
Empire Blue Cross Blue Shield HealthPlus
- Child/Family Health Plus
- Essential Plan
Fidelis Care
- Child/Family Health Plus
- Essential Plan
- Medicaid Managed Care
- Medicare Managed Care
Healthfirst
- Child/Family Health Plus
- Leaf (Exchange)
- Medicare Managed Care
Local 1199
- Local 1199
MagnaCare (National)
- MagnaCare
Medicare
- Railroad
- Traditional Medicare
Multiplan
- Multiplan
MVP Health Care
- Child/Family Health Plus
- Essential Plan
- HMO
- Medicaid Managed Care
Quality Health Management
- Quality Health Management
RiverSpring
- Special Needs
UnitedHealthcare
- Compass (Exchange)
- Empire Plan
- HMO
- Medicaid (Community Plan)
- Oxford Freedom
- Oxford HMO
- Oxford Liberty
- POS
- PPO
VNSNY CHOICE
- Medicare Managed Care
- SelectHealth
WellCare
- Medicare Managed Care
World Trade Center Health Plan
- World Trade Center Health Plan
Credentials & Experience
Education & Training
- MD, University of Pennsylvania School of Medicine
- 1988 University of Pennslyvania School of Medicine
- Internship: Barnes Jewish Hospital
- Residency: Barnes Jewish Hospital
- Fellowship: Memorial Sloan-Kettering Cancer Center
Committees, Societies, Councils
Southwest Oncology Group, Leukemia Committee and Leukemia Committee Working Group
Society of Hematologic Oncology, Education Committee
American Association of Cancer Research
American Society of Clinical Oncology, Scientific Program Committee on Leukemia, Myelodysplasia, and Transplantation
American Society of Hematology
Board Certifications
- Hematology
- Medical Oncology
Honors & Awards
- New York Magazine: Top Doctors Castle Connolly, 2014
- America's Top Doctors Castle Connolly, 2014, 2013, 2012, 2011, 2010
- Top Doctors: New York Metro Area Castle Connolly, 2015, 2014, 2013, 2011, 2010, 2009, 2007
- America's Top Doctors for Cancer Castle Connolly, 2014, 2013, 2012, 2011, 2010, 2009, 2008, 2007
- Louise and Allston Boyer Young Investigator Award for Distinguished Achievement in Biomedical Research Memorial Sloan-Kettering Cancer Center, 2001
- Super Doctor SuperDoctors.com
Research
Selected Publications
- Jurcic JG, Nimer SD, Scheinberg DA, DeBlasio T, Warrell RP Jr, Miller WH Jr. Prognostic significance of minimal residual disease detection and PML/RAR-a isoform type: Long-term follow-up in acute promyelocytic leukemia. Blood 2001; 98:2651-2656.
- Jurcic JG, Larson SM, Sgouros G, McDevitt MR, Finn RD, Divgi CR, Ballangrud Ã…M, Hamacher KA, Ma D, Humm JL, Brechbiel MW, Molinet R, Scheinberg DA. Targeted alpha particle immunotherapy for myeloid leukemia. Blood 2002; 100:1233-1239.
- Aliff TB, Maslak PB, Jurcic JG, Heaney ML, Cathcart KN, Sepkowitz KA, Weiss MA. Refractory aspergillus pneumonia in patients with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericin. Cancer 2003; 97:1025-1032.
- Feldman E, Kalaycio M, Weiner G, Frankel S, Schulman P, Schwartzberg L, Jurcic J, Velez-Garcia E, Seiter K, Scheinberg DA, Levitt D, Wedel N. Treatment of relapsed or refractory acute myeloid leukemia with humanized anti-CD33 monoclonal antibody HuM195. Leukemia 2003; 17:314-318.
- Burke JM, Caron PC, Papadopoulos EB, Divgi CR, Sgouros G, Panageas K, Finn RD, Larson SM, O'Reilly RJ, Scheinberg DA, Jurcic JG. Cytoreduction with iodine-131-anti-CD33 antibodies before bone marrow transplantation for advanced myeloid leukemias. Bone Marrow Transplant 2003; 32:549-556.
- Feldman EJ, Brandwein J, Stone R, Kalaycio M, Moore J, O'Connor J, Wedel N, Roboz GJ, Miller C, Chopra R, Jurcic JG, Brown R, Ehmann WC, Schulman P, Frankel SR, Scheinberg D. Phase III randomized multicenter study of a humanized anti-CD33 monoclonal antibody, lintuzumab, in combination with chemotherapy, versus chemotherapy alone in patients with refractory or first-relapsed acute myeloid leukemia. J Clin Oncol 2005; 23:4110-4116.
- Lamanna N, Jurcic JG, Noy A, Maslak PM, Gencarelli AN, Panageas KS, Heaney ML, Brentjens RJ, Golde D, Scheinberg DA, Zelenetz AD, Weiss MA. Sequential therapy with fludarabine, high-dose cyclophosphamide, and rituximab in previously untreated patients with chronic lymphocytic leukemia produces high quality responses: Molecular remissions predict for durable complete responses. J Clin Oncol 2009; 27:491-497.
- Raza A, Jurcic JG, Roboz GJ, Maris M, Stephenson JJ, Wood BL, Feldman EJ, Galili N, Grove LE, Drachman JG, Sievers EL. Complete remissions observed in acute myeloid leukemia following prolonged exposure to lintuzumab: a phase 1 trial. Leuk Lymph 2009; 50:1336-1344.
- Maslak PG, Dao T, Krug LM, Chanel S, Korontsvit T, Zakhaleva V, Zhang R, Wolchok JD, Yuan J, Pinilla-Ibarz J, Berman E, Weiss MA, Jurcic J, Frattini MG, Scheinberg DA. Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T cell responses in patients with complete remission from acute myeloid leukemia. Blood 2010; 116:171-179.
- Rosenblat TL, McDevitt MR, Mulford DA, Pandit-Taskar N, Divgi CR, Panageas K, Weiss MA, Chanel S, Morgenstern A, Sgouros G, Larson SM, Scheinberg DA, Jurcic JG. Sequential cytarabine alpha-particle immunotherapy with bismuth-213-lintuzumab (HuM195) for acute myeloid leukemia. Clin Cancer Res 2010; 16:5303-5311.
- Park JH, Qiao B, Panageas KS, Schymura MJ, Jurcic JG, Rosenblat TL, Altman JK, Douer D, Rowe JM, Tallman MS. Early death rate in acute promyelocytic leukemia remains high despite all-trans retinoic acid. Blood 2011; 118:1248-1254.
- Brentjens R, Riviere I, Park JH, Davila ML, Want X, Stefanski J, Taylor C, Yeh R, Bartido S, Borquez-Ojeda O, Olszewska M, Bernal Y, Pegram H, Przybylowski M, Hollyman D, Usachenko Y, Pirraglia D, Hosey J, Santos E, Halton E, Maslak P, Scheinberg D, Jurcic J, Heaney M, Heller G, Frattini M, Sadelain M. Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B cell leukemias. Blood 2011; 118:4817-4828.
- Sekeres MA, Lancet JE, Wood BL, Grove LE, Sandalic L, Sievers LE, Jurcic JG. Randomized, phase 2b study of low-dose cytarabine and lintuzumab versus low-dose cytarabine and placebo in older adults with untreated AML. Haematologica 2013 98:119-128.
- Goldberg JD, Linker A, Kuk D, Ratan R, Jurcic J, Barker JN, Castro-Malaspina HR, Giralt S, Hsu K, Jakubowski AA, Jenq R, Koehne G, Papadopoulos EB, van den Brink MRM, Young JW, Boulad F, Kernan NA, O'Reilly RJ, Yahalom J, Heller G, Perales M-A. T-cell depleted stem-cell transplantation for adults with high-risk acute lymphocytic leukemia in 1st complete remission: long-term survival with a decreased risk of graft-versus-host disease. Biol Blood Marrow Transplant 2013; 19:208-213.
- Brentjens RJ, Davila ML, Riviere I, Park J, Wang X, Cowell LG, Bartido S, Stefanski J, Taylor C, Olszewska M, Borquez-Ojeda O, Qu J, Wasielewska T, He Q, Bernal Y, Rijo IV, Hedvat C, Kobos R, Curran K, Steinherz P, Jurcic J, Rosenblat T, Maslak P, Frattini M, Sadelain M. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 20 March 2013; 5(177):177ra38.
- Altman JK, Rademaker A, Cull E, Weitner BB, Ofran Y, Rosenblat TL, Haidau A, Park JH, Ram S, Orsini J, Sandhu S, Catchatourian R, Trifilio SM, Adel NG, Frankfurt O, Stein EM, Mallios G, DeBlasio T, Jurcic JG, Nimer S, Peterson LC, Kwaan H, Rowe JM, Douer D, Tallman MS. Administration of ATRA to newly diagnosed patients with acute promyelocytic leukemia is delayed contributing to early hemorrhagic death. Leuk Res 2013; 37:1004-1009.Jurcic JG, Rosenblat TL. Targeted alpha-particle immunotherapy for acute myeloid leukemia. Am Soc Clin Oncol Educ Book. 2014:e126-31.
For a complete list of publications, please visit PubMed.gov