Jeremy R. Beitler, MD, MPH
Dr. Jeremy Beitler is a pulmonary intensivist and Director of Clinical Research for the Center for Acute Respiratory Failure at Columbia University. Clinically, he cares for patients admitted to the medical intensive care units (MICUs) at New York-Presbyterian Hospital / Columbia University Medical Center. His NIH-funded research program focuses on optimizing mechanical ventilatory support for patients with acute respiratory failure, including acute respiratory distress syndrome (ARDS).
ARDS occurs in up to one-quarter of all critically ill adults receiving mechanical ventilation. Despite considerable advances in understanding of disease pathogenesis, ARDS remains associated with high risk of death—up to 45% mortality for severe disease. The most effective proven therapy for ARDS is to limit the degree of lung stretch with each machine-supported breath. Yet, how best to personalize ventilatory support to each individual patient’s unique risk of lung injury is unclear. Dr. Beitler’s research seeks to address this gap by advancing understanding of the interaction between pulmonary biomechanics and lung biology. He uses advanced techniques such as esophageal manometry, electrical impedance tomography, and airway waveform analysis to quantify lung mechanics at bedside. These measures are paired with biological samples to identify dose-response between lung stretch and biological injury.
Dr. Beitler would like to express his gratitude to the many patients and families who have advanced this research by participating in clinical studies. He sincerely believes your essential support ultimately will help improve survival and decrease morbidity for patients suffering from acute respiratory failure.
Areas of Expertise / Conditions Treated
- Cardiac Arrest
- Critical Care
- Intensive Care
- Mechanical Ventilation
- Pulmonary Critical Care Medicine
- Pulmonary Disease
- Respiratory Failure
- Assistant Professor of Medicine at CUMC
- Director of Clinical Research, Center for Acute Respiratory Failure
- Director of Columbia Respiratory Critical Care Trials Group
- NewYork-Presbyterian / Columbia University Irving Medical Center
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- Great West (National)
- Medicare Managed Care
- Essential Plan
- Medicaid Managed Care
- Medicare Managed Care
- Select Care (Exchange)
- Local 1199
- Traditional Medicare
- Special Needs
- Compass (Exchange)
- Empire Plan
- Medicare Managed Care
Credentials & Experience
Education & Training
- MD, New York University School of Medicine
- Pennsylvania State University
- MPH, Harvard School of Public Health
- Residency: New York University Langone Medical Center
- Fellowship: Massachuetts General Hospital
- Pulmonary Disease
- Critical Care Medicine
- Internal Medicine
Honors & Awards
- 2018 Carmel Research Excellence Prize, Western Region, American Federation for Medical Research
- 2018 Faculty Teaching Award, University of California San Diego Medicine Chief Resident Selection
- 2016 Faculty Teaching Award, University of California San Diego Medicine Residency
- 2013 Fellow Teaching Award, Brigham & Women’s Hospital Residency
- 2010 Postgraduate Research Award, New York University Department of Medicine
- 2008 Award for Outstanding Community Service, Medical Society of the State of New York
- Acute Respiratory Distress Syndrome (ARDS)
- Acute Respiratory Failure
- Patient-ventilator dyssynchrony
- Post-cardiac arrest syndrome (PCAS)
- Sedation management
- Ventilation-induced lung and extrapulmonary organ injury
NIH ACTIV3-TESICO (Site PI: Beitler)
Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) 3b: Therapeutics for Severely Ill Inpatients with COVID-19
Department of Defense / Quantum Leap Healthcare Collaborative (Site PI: Beitler)
I-SPY COVID Trial: An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients
Canadian Institutes for Health Research (Site PI: Beitler)
Frequency of Screening and SBT Technique (FAST) Trial
NIH K23-HL133489 (PI: Beitler)
Breath stacking dyssynchrony in acute respiratory distress syndrome
NIH R21-HL145506 (PI: Beitler)
Measuring lung stress to identify occult ventilation-induced lung injury in ARDS
- Beitler JR, Sarge T, Banner-Goodspeed VM, Gong MN, Cook D, Novack V, Loring SH, Talmor D, EPVent-2 Study Group. Effect of titrating positive end-expiratory pressure (PEEP) with an esophageal pressure-guided strategy vs. an empiric high PEEP-FiO2 strategy on death and days free from mechanical ventilation among patients with acute respiratory distress syndrome: a randomized clinical trial. JAMA. 2019;321:846-857.
- Sarge T, Baedorf-Kassis E, Banner-Goodspeed V, Novack V, Loring SH, Talmor D, Beitler JR. Effect of esophageal pressure-guided positive end-expiratory pressure on survival from acute respiratory distress syndrome: a risk-based and mechanistic reanalysis of the EPVent-2 trial. American Journal of Respiratory and Critical Care Medicine. 2021.
- Beitler JR, Ghafouri TB, Jindasa SP, Mueller A, Hsu L, Anderson RJ, Joshua J, Tyagi S, Malhotra A, Sell RE, Talmor D. Favorable neurocognitive outcome with low tidal volume ventilation after cardiac arrest. American Journal of Respiratory and Critical Care Medicine. 2017;195:1198-1206.
- Beitler JR, Majumdar R, Hubmayr RD, Malhotra A, Thompson BT, Owens RL, Loring SH, Talmor D. Volume delivered during recruitment maneuver predicts lung stress in acute respiratory distress syndrome. Critical Care Medicine. 2016;44:91-99.
- Dzierba AL, Khalil AM, Derry K, Madahar P, Beitler JR. Discordance between respiratory drive and sedation depth in critically ill patients receiving mechanical ventilation. Critical Care Medicine. 2021.
- Beitler JR, Thompson BT, Baron RM, Bastarache JA, Denlinger LC, Esserman L, Gong MN, LaVange LM, Lewis RJ, Marshall JC, Martin TR, McAuley DF, Meyer NJ, Moss M, Reineck LA, Rubin E, Schmidt EP, Standiford TJ, Ware LB, Wong HR, Aggarwal NR, Calfee CS. Advancing precision medicine for acute respiratory distress syndrome. Lancet Respiratory Medicine. 2021.
- Abrams D, Montesi SB, Moore SKL, Manson D, Klipper KM, Case MA, Brodie D, Beitler JR. Powering bias and clinically important treatment effects in randomized trials of critical illness. Critical Care Medicine. 2020;48:1710-1719.
- Beitler JR, Mittel AM, Kallet R, Kacmarek R, Hess D, Branson R, Olson M, Garcia I, Powell B, Wang DS, Hastie J, Panzer O, Brodie D, Hill LL, Thompson BT. Ventilator sharing during an acute shortage caused by the Covid-19 pandemic. American Journal of Respiratory and Critical Care Medicine. 2020;202:600-604.