Fay Kastrinos, MD

Cancer Care, Genetic Counseling
More specialties
Accepting New Patients
Virtual Visits/Telehealth
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Women, Colon Cancer, Screening - Dr. Fay Kastrinos

Areas of Expertise / Conditions Treated

  • Breast Cancer Genetic Susceptibility
  • Cancer Genetics
  • Cancer Prevention
  • Gastrointestinal Cancer
  • Genetic Screening
  • Ovarian Cancer Genetic Susceptibility
  • Pancreatic Cancer

Academic Appointments

  • Associate Professor of Medicine at CUMC

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center


  • Female

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Virtual Visits/Telehealth

Virtual Visits allow you to connect with your provider from the comfort, convenience, and safety of your own home.

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Phone Appointments

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161 Fort Washington Avenue
Suite 862
New York, NY 10032

Insurance Accepted

Affinity Health Plan

  • Essential Plan
  • Medicaid Managed Care


  • Medicare Managed Care
  • Special Needs

Amida Care

  • Special Needs


  • EPO
  • Great West (National)
  • HMO
  • Medicare Managed Care
  • POS
  • PPO


  • Medicare Managed Care
  • PPO


  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross Blue Shield HealthPlus

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care

Fidelis Care

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care
  • Medicare Managed Care


  • Child/Family Health Plus
  • Leaf (Exchange)
  • Medicaid Managed Care
  • Medicare Managed Care

Local 1199

  • Local 1199

MagnaCare (National)

  • MagnaCare


  • Railroad
  • Traditional Medicare


  • Multiplan

MVP Health Care

  • Child/Family Health Plus
  • Essential Plan
  • HMO
  • Medicaid Managed Care

Quality Health Management

  • Quality Health Management


  • Special Needs


  • Compass (Exchange)
  • Empire Plan
  • HMO
  • Medicaid (Community Plan)
  • Medicare Managed Care
  • Oxford Freedom
  • Oxford HMO
  • Oxford Liberty
  • POS
  • PPO


  • Medicaid Managed Care
  • Medicare Managed Care

World Trade Center Health Plan

  • World Trade Center Health Plan

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Credentials & Experience

Education & Training

  • St. George's University School of Medicine (Grenada)
  • Residency: University of Massachusetts Medical Center
  • Fellowship: Brigham & Women's Hospital

Board Certifications

  • Gastroenterology


Dr. Kastrinos is a clinical gastroenterologist with interests related to the genetics, screening, and primary prevention of gastrointestinal tumors, primarily colorectal and pancreatic cancer. She has expertise in the genetic evaluation of patients at risk for hereditary gastrointestinal cancer syndromes and directs a multi-disciplinary specialty clinic at the Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, for genetic risk assessment and cancer prevention in familial gastrointestinal syndromes. She has expertise in clinical cancer genetics, statistical methodology involving the genetic epidemiology of cancer predisposition syndromes, development of prediction models, and analyses of large databases. Her research focus complements her clinical interests and involves optimizing the identification of patients with inherited cancer syndromes and promoting existing and testing novel cancer screening and prevention strategies. She has led large-scale studies, multiple national and international collaborations in developing tools to improve genetic risk assessment for inherited colorectal and pancreatic cancers and developing guidelines for optimal surveillance strategies for individuals at high risk for these cancers. She serves as site-PI at Columbia University for the (i) Cancer of the Pancreas Screening (CAPS) multicenter consortium (U01); (ii) Circulating Biomarker Consortium for the Early Detection of Pancreatic Cancer (U01); (iii) international prospective clinical trial for the validation of a novel biomarker for the early diagnosis of pancreatic cancer in high-risk individuals with familial pancreatic cancer (Immunovia-PanFAM1).

Selected Publications

  • Kastrinos F, Samadder NJ, Burt RW. Use of Family History and Genetic Testing to Determine Risk of Colorectal Cancer. Gastroenterology. 2020; 158(2):389-403. PMID: 31759928
  • Yurgelun MB, Kastrinos F. Tumor Testing for Microsatellite Instability to Identify Lynch Syndrome: New Insights Into an Old Diagnostic Strategy.J Clin Oncol. 2019; 37(4):263-265. PMID: 30550362
  • Hasan A, Moscoso DI, Kastrinos F. The role of genetics in pacreatitis. Gastrointest Endosc Clin N Am. 2018; 28(4):587-603. PMID: 30241646
  • Kastrinos F, Steyerberg EW, Mercado R, Balmaña J, Holter S, Gallinger S, Siegmund KD, Church JM, Jenkins MA, Lindor NM, Thibodeau SN, Burbidge LA, Wenstrup RJ, Syngal S. (2010) The PREMM 1,2,6 Model Predicts Risk of MLH1, MSH2, and MSH6 Germline Mutations Based on Cancer History.
  • Gastroenterology. Aug 18. :[Epub ahead of print]
  • Kastrinos F, Mukherjee B, Tayob N, Wang F, Sparr J, Raymond VM, Bandipalliam P, Stoffel EM, Gruber SB, Syngal S. (2009) Risk of pancreatic cancer in families with Lynch syndrome.
  • JAMA . 302:1790-5
  • Stoffel E, Mukherjee B, Raymond VM, Tayob N, Kastrinos F, Sparr J, Wang F, Bandipalliam P, Syngal S, Gruber SB. (2009) Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome.
  • Gastroenterology. 137:1621-7
  • Kastrinos F, Allen JI, Stockwell DH, Stoffel EM, Cook EF, Mutinga ML, Balmaña J, Syngal S. (2009) Development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy.
  • Am J Gastroenterol. 104:1508-18
  • Kastrinos F, Lebwohl B, Neugut AI. (2009) ACP Journal Club. CT colonography had 90% sensitivity and 86% specificity for diagnosing large adenomas and cancer in asymptomatic adults.
  • Ann Intern Med. 150:JC2-13
  • Kastrinos F, Stoffel EM, Balmaña J, Steyerberg EW, Mercado R, Syngal S. (2008) Phenotype comparison of MLH1 and MSH2 mutation carriers in a cohort of 1,914 individuals undergoing clinical genetic testing in the United States.
  • Cancer Epidemiol Biomarkers Prev. 17:2044-51
  • Kastrinos F, Syngal S. (2007) Recently identified colon cancer predispositions: MYH and MSH6 mutations.
  • Semin Oncol. 34:418-24
  • Kastrinos F, Stoffel EM,Balmaña J, Syngal S. (2007) Attitudes toward prenatal genetic testing in patients with familial adenomatous polyposis.
  • Am J Gastroenterol. 102:1284-90