
Overview
Dr. Leith Rankine is a board-certified medical physicist and an Associate Professor of Radiation Oncology at Columbia University Irving Medical Center. He joined Columbia University in September 2026 after more than a decade at the University of North Carolina at Chapel Hill, where he served as a clinical medical physicist, educator, researcher, and clinical leader. His clinical expertise includes image-guided radiation therapy (IGRT), stereotactic body radiation therapy (SBRT), respiratory motion management, and surface-guided radiation therapy (SGRT). He currently provides clinical services at NewYork-Presbyterian Hospital, Columbia University Irving Medical Center, NY.
Dr. Rankine earned his PhD and MS in Medical Physics from Duke University, an MS in Physics from Northeastern University, and a BS (Hons) in Physics from Curtin University in Australia. He completed his CAMPEP-accredited medical physics residency in radiation therapy at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis, Missouri. During his residency, he contributed to the clinical implementation of a novel single-room proton therapy system and real-time, real-anatomy tracking and gated radiation delivery on the first clinical MRI-guided radiation therapy system. After completing his residency, Dr. Rankine joined the Department of Radiation Oncology at the University of North Carolina at Chapel Hill, where he served as a clinical medical physicist and faculty member for more than a decade. During his time at UNC, he held clinical leadership roles in IGRT, respiratory motion management, SGRT, linac-based SBRT, and linear accelerator quality assurance (QA). In addition, Dr Rankine worked with physician faculty to clinically implement specialized treatment techniques, such as GRID therapy, stereotactic arrhythmia radioablation (STAR), and bolus electron conformal therapy (BECT). He was also actively involved in medical physics education and residency training, serving as Associate Director of the CAMPEP-accredited medical physics residency program and the primary mentor for several clinical rotations.
Dr. Rankine's research interests include functional imaging for personalized radiation therapy and GRID therapy for extremity sarcoma. In particular, his research has investigated the use of hyperpolarized xenon-129 magnetic resonance imaging to characterize regional lung function, guide functional avoidance treatment planning, and better understand radiation-induced lung injury in patients receiving thoracic radiation therapy. He is also an active volunteer with the American Board of Radiology, serving on the Therapeutic Medical Physics Qualifying Committee.
Academic Appointments
- Associate Professor of Radiation Oncology (Physics) at CUIMC
Credentials & Experience
Education & Training
- BS (with Honors), 2009 Physics, Curtin University of Technology, Department of Imaging and Applied Physics, Perth, Australia
- MS, 2011 Physics, Northeastern University, Department of Physics, Boston, MA
- MS, 2013 Medical Physics, Northeastern University, Department of Physics, Boston, MA
- PhD, 2021 Medical Physics, Duke University, Medical Physics Graduate Program, Durham, NC
- Residency: 2015 Therapeutic Medical Physics, Washington University in St. Louis/Barnes-Jewish Hospital, Saint Louis, MO
Committees, Societies, Councils
Member, American Association of Physicists in Medicine (AAPM)
Associate Member, American Society for Radiation Oncology (ASTRO)
Vice Chair, Working Group for AAPM’s Medical Physics Practice Guideline (MPPG) 19: Recommendations for implementing X-ray-guided respiratory motion management systems on a conventional linear accelerator.
Committee Member & Item Writer, American Board of Radiology (ABR) Therapeutic Medical Physics Qualifying Committee
Honors & Awards
Physics Mentorship Award, University of North Carolina at Chapel Hill, 2018, 2020, 2023, & 2025
ISMRM Summa Cum Laude Merit Award, 2020 ISMRM & SMRT Virtual Conference & Exhibition, 2020
Excellence in Teaching Assistantship Award, Medical Physics Graduate Program, Duke University, 2020
“Best in Physics” for Joint Imaging/Therapy, American Association of Physicists in Medicine (AAPM), 59th Annual Meeting, Denver, CO, 2017
Annual Meeting Travel Award, Physics category, American Society for Radiation Oncology (ASTRO), 59th Annual Meeting, San Diego, CA, 2017
Chancellor’s Scholarship Recipient, Duke University Graduate School, 2016
Academic Excellence Award, Duke University Medical Physics Graduate Program, 2012 & 2013
Excellence in Research Award, Duke University Medical Physics Graduate Program, 2013
Lawrence Award for Excellence in Teaching, Department of Physics, Northeastern University, 2010 & 2011
Recognition of Academic Achievement, Curtin University of Technology, Perth, Western Australia, 2006, 2008, & 2009
Research
Selected Publications
Rankine, L.J., Lu, J., Wang, Z., Kelsey, C.R., Marks, L., Das, S.K., & Driehuys, B. (2024). Quantifying regional radiation-induced lung injury in patients using hyperpolarized xenon-129 gas exchange magnetic resonance imaging. IJROPB, 120(1):216-228. https://doi.org/10.1016/j.ijrobp.2024.02.049
Rankine, L.J., Wang, Z., Kelsey, C.R., Bier, E., Driehuys, B., Marks, L., & Das, S.K. (2021). Hyperpolarized 129Xe Magnetic Resonance Imaging for Functional Avoidance Treatment Planning in Thoracic Radiation Therapy: A Comparison of Ventilation- and Gas Exchange-Guided Treatment Plans. IJROBP, 111(4):1044-1057. https://doi.org/10.1016/j.ijrobp.2021.07.002
Green, O.L., Rankine, L.J., Cai, B., Curcuru, A., Kashani, R., Rodriguez, V., Li, H.H., Parikh, P.J., Robinson, C.G., Olsen, J.R., Mutic, S., Goddu, S.M., & Santanam, L. (2018). First clinical implementation of real-time, real anatomy tracking and radiation beam control. Med. Phys., 45(8):3728-3740. https://doi.org/10.1002/mp.13002
Rankine, L.J., Wang, Z., Driehuys, B., Marks, L.B., Kelsey, C., & Das, S.K. (2018). Correlation of Regional Lung Ventilation and Gas Transfer to Red Blood Cells: Implications for Functional-Avoidance Radiation Therapy Planning. Int. J. Radiation Oncol. Biol. Phys. 101(5):1113-1122. https://doi.org/10.1016/j.ijrobp.2018.04.017
Hu, Y., Rankine, L., Green, O., Kashani, R., Li, H.H., Li, H., Nana, R., Rodriguez, V., Santanam, L., Shvartsman, S., Victoria, J., Wooten, H.O., Dempsey, J.F., & Mutic, S. (2015). Characterization of the onboard imaging unit for the first clinical magnetic resonance image guided radiation therapy system. Med. Phys. 42:(10):5828-5837. https://doi.org/10.1118/1.4930249
For a complete list of publications, please visit PubMed.gov