Motor Neuron Center News Search
-
In spinal muscular atrophy, a neurodegenerative disease caused by ubiquitous deficiency in the survival motor neuron (SMN) protein.
-
Source:
The ALS Association
The ALS Association and Target ALS are pleased to announce the launch of a new collaborative effort to expand the collection of biofluids from people with ALS.
-
Using advanced DNA sequencing methods, researchers have identified a new gene that is associated with sporadic amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease.
-
Source:
Wiley Online Library
Motor function in mammalian species depends on the maturation of spinal circuits formed by a large variety of interneurons that regulate motoneuron firing and motor output.
-
Verge Genomics, a drug discovery company utilizing genomic data for neuroscience therapeutics, has established a multi-institution industry-academic collaboration with four top universities.
-
The mechanisms by which mutations in FUS and other RNA binding proteins cause ALS and FTD remain controversial.
-
Source:
Nature Communications
Mutations in FUS cause amyotrophic lateral sclerosis (ALS), including some of the most aggressive, juvenile-onset forms of the disease.
-
An expanded GGGGCC hexanucleotide in C9ORF72 (C9) is the most frequent known cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
-
Spinal muscular atrophy (SMA) is a common and oft-fatal pediatric neuromuscular disorder caused by insufficient SMN protein.
-
Along with Parkin, PINK1 plays a critical role in maintaining mitochondrial quality control.
