Challenges in Management of Bladder and Prostate Cancer in 2021: What Happens When the Standard of Care is Not Enough?  This symposium will focus on updating practitioners on recent developments in the management of high risk localized prostate cancer, BCG unresponsive nonmusclei invasive bladder cancer as well as the multidisciplinary management of muscle invasive bladder cancer. These updates will include descriptions of the epidemiology of these entities as well as recently published data describing innovative ways of managing these three clinical disease states. A particular focus will be placed on ongoing clinical trials available at Columbia University’s Herbert Irving Cancer Center. The target audience of this seminar will include practicing Urologists, medical oncologists, radiation oncologists, nurse practitioners, and trainees interested in prostate and bladder cancer care. Upon conclusion of this activity, participants will be better able to: 1. Recognize high risk localized prostate cancer and its treatment options including surgery, radiation, and neoadjuvant systemic therapies. 2. Define the disease state known as BCG unresponsive bladder cancer and review the available FDA approved as well as clinical trial therapies in this space. 3. Describe the results of neoadjuvant chemotherapy for muscle invasive bladder cancer and elaborate on the role of systemic immunotherapy in this setting. FACULTY Christopher B. Anderson, MD, MPH Assistant Professor of Urology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY Guarionex Joel Decastro, MD, MPH, Assistant Professor of Urology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY James M. McKiernan, MD, John K. Lattimer Professor of Urology; Director, Urologic Oncology; Chair, Department of Urology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY Catherine S. Spina, MD, PhD, Assistant Professor of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY Mark N. Stein, MD, Associate Professor of Medical Oncology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY AGENDA 5:00 PM Welcome James M. McKiernan, MD 5:05 PM High Risk Localized Prostate Cancer: Updates in Multidisciplinary Care Christopher B. Anderson, MD, MPH & Catherine S. Spina, MD, PhD 5:25 PM BCG Unresponsive High Risk Non-Muscle Invasive Bladder Cancer: An Expanding Menus of Options Guarionex Joel Decastro, MD, MPH 5:45 PM Muscle Invasive Bladder Cancer: It’s Not Just Cystectomy Anymore Mark N. Stein, MD 6:05 PM Q&A 6:30 PM Adjourn This activity has been approved for AMA PRA Category 1 Credit™

This program includes an overview of mentoring fundamentals and active learning exercises, followed by a panel discussion and Q&A. Moderator: Daichi Shimbo Professor of Medicine Director of Training and Education (TRANSFORM) Resource Irving Institute for Clinical and Translational Research  Associate Dean for Research Career Development Panelists: Joan M. Bathon, MD Professor of Medicine Advisory Dean for Clinician-Scientist Faculty Lauren S. Chernick, MD Assistant Professor of Pediatric (in Emergency Medicine) at the Columbia University Medical Center Angela M. Christiano, PhD Richard and Mildred Rhodebeck Professor of Dermatology and Professor of Genetics and Development Advisory Dean for Basic Scientist Faculty Laura Lennihan, MD Professor of Neurology at the Columbia University Medical Center Advisory Dean for Clinician-Educator Faculty Rini B. Ratan, MD Professor of Obstetrics and Gynecology at the Columbia University Medical Center Advisory Dean for Clinician-Educator Faculty Marisa Spann Associate Professor of Medical Psychology (in Psychiatry and Pediatrics) Robert A. Whittington, MD Professor of Anesthesiology at the Columbia University Medical Center Assistant Dean for Academic Development, Faculty Diversity and Inclusion

Simon K. Cheng, MD, PhD, Residency Program Director and Assistant Professor of Radiation Oncology Naiyer A. Rizvi, MD, Professor of Medicine at CUMC Catherine A. Shu, MD, Professor of Medicine at CUMC Joshua R. Sonett, MD, Edward C. and Anne K. Weiskopf Professor of Surgical Oncology (in Surgery) at CUMC This activity has been approved for AMA PRA Category 1 Credit™

People with psychiatric disorders may have cognitive impairments that affect their ability to function in daily life, and benefit from psychiatric interventions. Cognitive skills training directly targets impaired cognitive processes seen across a variety of psychiatric conditions and thereby seeks to improve behavioral functioning. This conference will provide a forum for academic researchers, clinicians, and students to learn about evidence-based cognitive interventions. Research symposia will spotlight novel treatment approaches and inform key issues pertinent to treatment implementation and effectiveness. A clinical workshop will provide expert guidance in translating evidence-based cognitive remediation approaches for virtual delivery. Upcon conclusion of the activity, participants will be better able to: 1. Identify cognitive deficits, motivation deficits that interact with cognitive deficits, and how both can be targeted in recovery-oriented treatments for people with psychiatric disorders 2. Identify integrative intervention approaches to improve cognitive health, mental health, and functional outcomes in people with psychiatric disorders 3. Summarize factors that impact engagement in cognitive treatments and potential strategies to facilitate motivation and cognitive learning 4. Describe challenges to implementing empirically based cognitive interventions in routine settings and approaches to overcome them 5. Summarize how to provide remote cognitive health care