Stem Cell Biology

The Stem Cell Biology PhD track in the Biomedical Life Sciences Program investigates the unique properties of stem cells and their role in tissue development, maintenance, and repair, linking fundamental mechanisms of cell fate and differentiation to regenerative processes across the lifespan. Combining basic and translational perspectives, the track trains students in stem cell biology, regenerative medicine, and emerging technologies such as reprogramming, gene editing, bioengineering, and computational approaches, preparing them to drive innovations in both academic research and therapeutic development.

Course Work

Common Program Course Work 

Each student must complete 2 required core research courses, 3 foundations courses, and participate in Research In Progress. At least one course from the Life Sciences Foundations and Computational Foundations series is required as part of the three foundations course requirement.

Core Research Courses 

Responsible Conduct of Research, Biomedical Research

Life Sciences  

Foundations

Molecules to Life I: Biochemistry & Molecular Biology (4 credits) and 

Molecules to Life II: Cell Biology & Genetics (4 credits)

Computational Foundations

Bytes to Biology and Health I: Quantitative methods in biology (4 credits) or 

Bytes to Biology and Health II: Quantitative and information theory in biology (4 credits) 

Research in Progress 

Research in Progress (1 credit per semester for 10 semesters) 

Track Specific Coursework 

Course requirements for students who commit to the Computational Biology Track:

  1. Stem Cells, Genome Engineering, and Regenerative Medicine (BMEN6510, 3 credits) 
  2. Advanced Topics in Stem Cells and Regeneration (NEW, 3 credits) 
  3. Elective: choose from any VP&S graduate course 

Skills & Competencies 

The VIBRE programs requires PhD candidates demonstrate proficiency in the following key scientific skills: Coding, Statistics, Scientific Writing, Oral Communication and Literature Review. These requirements may be met in multiple ways, including: 

  • Prior Experience: Students with strong undergraduate or graduate-level experience can meet requirements by demonstrating proficiency (e.g., a high grade in a relevant course). 
  • Coursework: Students may meet requirements through designated Columbia University courses. 
  • Track-based Activities: Communication and literature review skills may be developed through journal clubs, work-in-progress meetings, or specialized track-level courses. 

The director of graduate studies (DGS) of each student's program will track and document their progress toward these competencies. 

Other Curricular Requirements 

  • Orientation & Boot Camp – These programs offer students a comprehensive introduction to the Columbia University community and the VIBRE PhD Pathway.
  • Advising – Students regularly meet with faculty mentors and program advisors to guide their academic and research decisions, address core research skills, and discuss expectations and needs.
  • Research Rotations – During their first year, students complete at least three research rotations, each lasting about three months, in the labs of training faculty. Students select rotations based on their interests. These experiences help them explore potential dissertation mentors while expanding both their practical skills and theoretical understanding in different areas of research. 
  • First-Year Affiliation and Track Specialization – Students are affiliated with a track of interest during their first year, with formal selection of a program track occurring at the end of the first year.