Cancer Biology

The Cancer Biology PhD Track investigates the molecular, genetic, and cellular mechanisms that drive tumor initiation and progression, encompassing cancer cell–intrinsic programs such as genomics, epigenetics, and metabolism, as well as extrinsic influences from the tumor microenvironment and the immune system. Columbia's HICCC, translational expertise, and advanced core facilities, the track trains students to integrate mechanistic insights with cutting-edge technologies to develop new diagnostics and therapies, preparing them for diverse careers across academia, industry, and clinical research.

Course Work 

Common Program Course Work 

Each student must complete two required core research courses, three foundations courses, and participate in Research In Progress. At least one course from the Life Sciences Foundations and Computational Foundations series is required as part of the three foundations course requirement.   

Core Research Courses 

Responsible Conduct of Research, Biomedical Research

Life Sciences Foundations

Molecules to Life I: Biochemistry & Molecular Biology (4 credits) and 

Molecules to Life II: Cell Biology & Genetics (4 credits)

Computational Foundations

Bytes to Biology and Health I: Quantitative methods in biology (4 credits) or 

Bytes to Biology and Health II: Quantitative and information theory in biology (4 credits) 

Research in Progress 

Research in Progress (1 credit per semester for 10 semesters) 

Track Specific Coursework 

Course requirements for students who commit to the Cancer Biology Track

  1. Cancer Biology I (PATH4500, 3 credits) 
  2. Cancer Biology II (PATH4501, 3 credits) 
  3. Elective (3 credits): Choose from any VP&S graduate course 

Skills & Competencies 

The VIBRE programs require PhD candidates to demonstrate proficiency in the following key scientific skills: Coding, Statistics, scientific writing, Oral Communication, and Literature Review. 

These requirements may be met in multiple ways, including:

  • Prior Experience: Students with strong undergraduate or graduate-level experience can meet requirements by demonstrating proficiency (e.g., a high grade in a relevant course). 
  • Coursework: Students may meet requirements through designated Columbia University courses. 
  • Track-based Activities: Communication and literature review skills can be developed through journal clubs, work-in-progress meetings, or specialized track-level sessions for students. The sstudent'sprogress toward these competencies will be documented by the pprogram'sDirector of Graduate Studies (DGS). 

Other Curricular Requirements 

Orientation & Boot Camp–These programs offer students a comprehensive introduction to the Columbia University community and the VIBRE PhD Pathway.

Advising–Students regularly meet with faculty mentors and program advisors to guide their academic and research decisions, address core research skills, and discuss expectations and needs.

Research Rotations—During their first year, students complete at least three research rotations, each lasting about three months, in the labs of training faculty. Students select rotations based on their interests. These experiences help them explore potential dissertation mentors while expanding both their practical skills and theoretical understanding in different areas of research. 

First-Year Affiliation and Track Specialization – Students are affiliated with a track of interest during their first year, with formal selection of a program track occurring at the end of the year.