The COMBO study tracks mothers and children across multiple health domains. Below is a snapshot of our enrollment totals, the follow-up activities completed so far, and what we measure. (Data as of 1/9/2026)
Enrollment Totals
Site
|
Enrolled
|
Alabama
|
87
|
New York
|
1.373
|
Utah
|
243
|
Total
|
1,703
|
Surveys Total Completed
Timepoint
|
Amount
|
2 months
|
756
|
4 months
|
894
|
6 months
|
874
|
9 months
|
545
|
18 months
|
661
|
24 months
|
718
|
36 months
|
Child
|
698
|
Maternal
|
630
|
48 months
|
Child
|
575
|
Maternal
|
502
|
Ambulatory Mood Assessment Survey
Timepoint
|
Completed
|
Prenatal
|
8
|
0 – 1 month
|
13
|
1 – 3 months
|
26
|
3 –5 months
|
28
|
Visits (Home & Video) Totals
Timepoint (type of visit)
|
Measures
|
Completed
|
4 months (video)
|
Early Relational Health (ERH) & maternal sensitivity, still face/mask paradigm
|
606
|
4 months (in person)
|
ERH & physiology
|
39
|
9 months - Visit 1
|
Maternal cognition
|
630
|
9 months - Visit 2
|
ERH, child development
|
616
|
12–18 months (office)
|
ERH, Strange Situation Procedure (SSP)
|
30
|
24 months - Visit 1
|
Child development
|
455
|
24 months - Visit 2
|
ERH
|
430
|
36 months - Visit 1
|
ERH, theory of mind, inhibitory control, grit, temperament
|
412
|
36 months - Visit 2
|
ERH, theory of mind, inhibitory control, emotion matching, emotion regulation,
developmental milestones, nutrition
|
374
|
36 months - Visit 3
|
Mealtime observation
|
348
|
48 months - Visit 1
|
ERH, infantile amnesia, book reading, frustration, cooperation
|
406
|
48 months - Visit 2
|
Memory
|
360
|
Other Measures
Physiological & Neuroimaging
|
MRI
|
Mom: 162 completed
|
Baby: 79 completed
|
Dyad: 77 completed
|
QMR
|
|
Biospecimens: Cord blood, placental tissue, maternal blood
|
78
|
Behavioral & Sensory
|
Smell tests
|
457
|
Socialization Goals Inventory (SGI) Interview
|
85
|
Qualitative & Psychosocial
|
Qualitative Interviews (NOSI)
|
64 completed
|
