The COMBO study tracks mothers and children across multiple health domains. Below is a snapshot of our enrollment totals, the follow-up activities completed so far, and what we measure. (Data as of 10/31/2025)
Enrollment Totals
Site
|
Enrolled
|
Alabama
|
87
|
New York
|
1.373
|
Utah
|
243
|
Total
|
1,703
|
Surveys Total Completed
Timepoint
|
Amount
|
2 months
|
756
|
4 months
|
894
|
6 months
|
874
|
9 months
|
533
|
18 months
|
652
|
24 months
|
704
|
36 months
|
Child
|
693
|
Maternal
|
624
|
48 months
|
Child
|
560
|
Maternal
|
489
|
Postnatal Ambulatory Mood Assessment Survey
Timepoint
|
Completed
|
0 – 1 month
|
13
|
1 – 3 months
|
26
|
3 –5 months
|
28
|
Visits (Home & Video) Totals
Timepoint (type of visit)
|
Measures
|
Completed
|
4 months (video)
|
Early Relational Health (ERH) & maternal sensitivity
|
606
|
4 months (in person)
|
ERH & physiology
|
39
|
9 months - Visit 1
|
Maternal cognition
|
617
|
9 months - Visit 2
|
ERH & child development
|
603
|
12–18 months (office)
|
ERH, Strange Situation Procedure (SSP) & mock pediatric visit
|
6
|
12–18 months (home)
|
SSP
|
6
|
24 months - Visit 1
|
Child development
|
450
|
24 months - Visit 2
|
ERH
|
426
|
36 months - Visit 1
|
ERH, theory of mind, inhibitory control, grit & temperament
|
426
|
36 months - Visit 2
|
ERH, theory of mind, inhibitory control, emotion matching, emotion regulation,
developmental milestones & nutrition
|
372
|
36 months - Visit 3
|
Mealtime observation
|
346
|
48 months - Visit 1
|
ERH, inhibitory control, infantile amnesia, frustration, cooperation & book reading
|
358
|
48 months - Visit 2
|
Memory
|
324
|
Other Measures
Physiological & Neuroimaging
|
MRI
|
Mom: 162 completed
|
Baby: 79 completed
|
Dyad: 77 completed
|
QMR
|
|
Maternal blood
|
|
Behavioral & Sensory
|
Smell tests
|
147
|
Socialization interviews
|
|
Qualitative & Psychosocial
|
Maternal oral interviews
|
64 completed
|
